Serine/threonine kinases and E2-ubiquitin conjugating enzymes in Planctomycetes: unexpected findings
Aida Arcas, I. Cases, A. Rojas
semanticscholar +1 more source
In Vivo Biosynthesis and Direct Incorporation of Non‐Canonical Amino Acids into Proteins
Autonomous cells are engineered biological systems capable of biosynthesising and directly incorporating non‐canonical amino acids (ncAAs) into proteins. These systems have the potential to extend the applicability of the genetic code to enable large‐scale fermentative production of proteins carrying ncAAs.
Ivana Drienovska+2 more
wiley +1 more source
The N-terminal extension of UBE2E ubiquitin-conjugating enzymes limits chain assembly.
Frances-Rose Schumacher+2 more
semanticscholar +1 more source
Internal Ubiquitin Electrophiles for Covalent Trapping and Inhibition of Deubiquitinases
The ubiquitin (Ub) system governs vital cellular processes in eukaryotic biology through an intricate network of Ub‐protein interactions. While semisynthetic C‐terminal Ub electrophiles (UbEs) are widely used to study Ub transfer and deubiquitinase (Dub) activity, they are limited to probing the active site while leaving other functionally important ...
Chittaranjan Das+7 more
wiley +1 more source
The family of ubiquitin‐conjugating enzymes (E2s): deciding between life and death of proteins
S. V. Wijk, H. Timmers
semanticscholar +1 more source
Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools
This study unveils a novel synthetic platform by solid‐phase peptide synthesis for generating FUBI‐based chemical tools to investigate FUBIylation, a poorly understood ubiquitin‐like signaling process linked to cancer. By employing these innovative probes, we uncover novel FUBI interactors, paving the way for transformative insights into FUBI biology ...
Francesca D’Amico+8 more
wiley +1 more source
Importin-11, a nuclear import receptor for the ubiquitin-conjugating enzyme, UbcM2
Scott M. Plafker
openalex +2 more sources
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard+29 more
wiley +1 more source
The Ubiquitin-Conjugating DNA Repair Enzyme HR6A Is a Maternal Factor Essential for Early Embryonic Development in Mice [PDF]
Henk P. Roest+8 more
openalex +1 more source