This study investigated how pomegranate juice affects inflammation in patients with inflammatory bowel disease who are currently in remission. After 12 weeks of drinking pomegranate juice, patients showed reduced markers of intestinal inflammation.
Ilaria Minato+25 more
wiley +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Synergistic effect of two E2 ubiquitin conjugating enzymes in SCF(hFBH1) catalyzed polyubiquitination. [PDF]
Kim JH+7 more
europepmc +1 more source
The Ubiquitin Conjugating Enzyme, UbcM2, Engages in Novel Interactions with Components of Cullin-3 Based E3 Ligases [PDF]
Kendra S. Plafker+2 more
openalex +1 more source
Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella+6 more
wiley +1 more source
A Functional Analysis of the Yeast Ubiquitin Ligase Rsp5: The Involvement of the Ubiquitin-Conjugating Enzyme Ubc4 and Poly-Ubiquitination in Ethanol-Induced Down-Regulation of Targeted Proteins [PDF]
Hiroyuki Hiraishi+3 more
openalex +1 more source
Computational Analysis of the Mechanism of the Ubiquitin Conjugating Enzyme Ubc13 [PDF]
Serban Zamfir+3 more
openaire +2 more sources
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou+8 more
wiley +1 more source
Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import
Scott M. Plafker+3 more
openalex +1 more source