Results 291 to 300 of about 63,885 (332)

CRISPR/Cas‐Mediated Gene Editing in Plant Immunity and Its Potential for the Future Development of Fungal, Oomycete, and Bacterial Pathogen‐Resistant Pulse Crops

Plant, Cell &Environment, EarlyView.
ABSTRACT Pulses provide myriad health benefits and are advantageous in an environmental context as a result of their leguminous nature. However, phytopathogenic fungi, oomycetes and bacteria pose a substantial threat to pulse production, at times leading to crop failure.
Stacy D. Singer, Mohammed M. Mukthar, Udaya Subedi, Hari Poudel, Guanqun Chen, Nora Foroud, Syama Chatterton   +6 more
wiley   +1 more source

New Integrative Vectors Increase Agrobacterium rhizogenes Transformation and Help Characterise Roles for Soybean GmTML Gene Family Members

Plant, Cell &Environment, EarlyView.
ABSTRACT Hairy‐root transformation is widely used to generate transgenic plant roots for genetic functional characterisation studies. However, transformation efficiency can be limited, largely due to the use of binary vectors. Here, we report on the development of novel integrative vectors that significantly increase the transformation efficiency of ...
Huanan Su, Mengbai Zhang, Estelle B. Grundy, Brett J. Ferguson   +3 more
wiley   +1 more source

Ubiquitin-proteasome system: a potential participant and therapeutic target in antiphospholipid syndrome. [PDF]

Front Immunol
Wang H, Tan Y, Liu Q, Yang S, Cui L.
europepmc   +1 more source

ISGylation and E3 ubiquitin ligases: an Atlantic salmon genetic perspective. [PDF]

Front Immunol
Grimholt U, Sindre H, Sundaram AYM.
europepmc   +1 more source

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Ubiquitin-conjugating enzyme genes in Oesophagostomum dentatum

Parasitology Research, 2006
Full-length genes representing different isoforms of the ubiquitin-conjugating enzyme UBC-2 were isolated from Oesophagostomum dentatum, cloned and sequenced. The alignment of their sequences (designated Od-ubc-2.1 to Od-ubc-2.3) revealed nucleotide variation at three positions within the predicted open reading frame of 444 bp.
Alasdair J. Nisbet, Youssef G. Abs EL-Osta, Pauline A. Cottee, Robin B. Gasser   +3 more
openaire   +3 more sources

Conformational Flexibility of a Ubiquitin Conjugation Enzyme (E2)

Biochemistry, 1999
Ubiquitination plays important roles in a variety of biological processes, such as DNA repair, cell cycle regulation, and p53-dependent processes. Despite intensive studies in ubiquitination, the mechanism of substrate recognition is still not well understood.
Binghui Shen, David J. Chen, Yuan Chen, Yate Ching Yuan, Qin Liu, Qin Liu   +5 more
openaire   +3 more sources

Ubiquitin-conjugating enzyme E2C: A potential cancer biomarker

The International Journal of Biochemistry & Cell Biology, 2014
The ubiquitin-conjugating enzymes 2C (UBE2C) is an integral component of the ubiquitin proteasome system. UBE2C consists of a conserved core domain containing the catalytic Cys residue and an N-terminal extension. The core domain is required for ubiquitin adduct formation by interacting with the ubiquitin-fold domain in the E1 enzyme, and contributes ...
Qihan Dong, Qihan Dong, Mu Yao, Chanlu Xie, Jianmin Wu, Christopher J. Powell   +5 more
openaire   +4 more sources

Characterization of the mouse ubiquitin-conjugating enzyme gene UbcM4

Mammalian Genome, 1999
The ubiquitination pathway targets not only normal (short-lived) intracellular eukaryotic proteins for degradation when appropriate, but also serves to eliminate mutant/misfolded proteins from the cell. An understanding of the molecular basis of the interaction between the ubiquitin-conjugating enzymes (E2s), ubiquitin protein ligases (E3s), and target
Stephen A. Rose, Philip A. Robinson, Helen C. Ardley, Ulrike Nuber, Alexander F. Markham, Martin Scheffner, Terry P. Moynihan   +6 more
openaire   +3 more sources

QRI8, a novel ubiquitin-conjugating enzyme in Saccharomyces cerevisiae

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1992
We have cloned and sequenced the gene encoding a novel ubiquitin-conjugating enzyme in Saccharomyces cerevisiae. Disruption of this gene shows that it is not essential for cell viability.
Estelle Decoster, Gérard Faye, Anne Vassal, Annick Boulet   +3 more
openaire   +3 more sources