Results 301 to 310 of about 63,885 (332)

Characterization of a human ubiquitin-conjugating enzyme gene UBE2L3

Mammalian Genome, 1996
Ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. We have identified a human gene, UBE2L3, localized on Chromosome (Chr) 22q11.
J. P. Leek, Philip A. Robinson, T. P. Moynihan, N. S. Brindle, J. Thompson, Alex F. Markham, H. C. Ardley   +6 more
openaire   +3 more sources

Ubiquitin-conjugating enzymes: novel regulators of eukaryotic cells

Trends in Biochemical Sciences, 1990
Covalent attachment of ubiquitin to cellular proteins is essential for cell viability and is catalysed by a set of distinct ubiquitin-conjugating enzymes. Individual members of this novel enzyme family mediate strikingly diverse functions, including DNA repair, cell cycle control, selective protein degradation and essential functions of the stress ...
Stefan Jentsch, Wolfgang Seufert, Hans-Albert Reins, Thomas Sommer   +3 more
openaire   +3 more sources

Tertiary structures of class I ubiquitin-conjugating enzymes are highly conserved: crystal structure of yeast Ubc4.

Biochemistry, 1993
The three-dimensional structure of a yeast ubiquitin-conjugating enzyme, encoded by the Saccharomyces cerevisiae UBC4 gene, has been determined at 2.7 A.
W. Cook, Leigh C. Jeffrey, Yuping Xu, V. Chau   +3 more
semanticscholar   +1 more source

Location of ubiquitin conjugates and ubiquitin-conjugating enzymes in rabbit brain.

1991
The work reports the location of ubiquitin conjugates and ubiquitin-conjugating enzymes in homogenates of rabbit brain.
MAGNANI, MAURO, SERAFINI, GIORDANO, ANTONELLI, ANTONELLA, CRINELLI, RITA, Manuela Malatesta, Giancarlo Gazzanelli   +5 more
openaire   +2 more sources

Structure of ubiquitin-conjugating enzyme 9 displays significant differences with other ubiquitin-conjugating enzymes which may reflect its specificity for sumo rather than ubiquitin.

Acta Crystallographica Section D: Biological Crystallography, 1998
The three-dimensional structure of ubiquitin-conjugating enzyme 9 (Ubc9) has been obtained to a resolution of 2.8 A by molecular replacement followed by a combination of automated refinement and graphical intervention. Diffraction data were recorded on a
M. Giraud, J. Desterro, J. Naismith
semanticscholar   +1 more source

E2 ubiquitin-conjugating enzymes in cancer: Implications for immunotherapeutic interventions.

Clinica chimica acta; international journal of clinical chemistry, 2019
S. M. Hosseini, Isobel S Okoye, Mitra Ghasemi Chaleshtari, Bita Hazhirkarzar, J. Mohamadnejad, G. Azizi, M. Hojjat-Farsangi, H. Mohammadi, S. Shotorbani, F. Jadidi‐Niaragh   +9 more
semanticscholar   +1 more source

Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins

Nature Chemistry, 2020
R. Hofmann, G. Akimoto, T. Wucherpfennig, C. Zeymer, J. Bode   +4 more
semanticscholar   +1 more source

Structure and function of ubiquitin-conjugating enzymes

WIT Transactions on Biomedicine and Health, 2014
Jie Ke Ming, Ying Mu Ying, Wu Xin Yin, Hu Tian, Huang Chun Hong, Yan Nian long   +5 more
openaire   +2 more sources

Matching the kinetics of natural enzymes with a single-atom iron nanozyme

Nature Catalysis, 2021
Dingsheng Wang, Juncai Dong, Lin Gu
exaly  

Confining enzymes in porous organic frameworks: from synthetic strategy and characterization to healthcare applications

Chemical Society Reviews, 2022
Guosheng Chen, Gangfeng Ouyang
exaly