Results 191 to 200 of about 81,275 (289)

The Genetic Wiring of Plant Trichomes: From Initiation to Fate Specification

Advanced Science, EarlyView.
Plant trichomes are not just simple hairs but metabolic powerhouses shaped by complex genetic programs. While the MYB‐bHLH‐WD40 module is well studied in Arabidopsis, recent findings reveal that HD‐Zip IV transcription factors drive multicellular and glandular trichome development through dose‐dependent mechanisms.
Meng Li, Yuanbo Huang, Yadi Du, Shuang Wu   +3 more
wiley   +1 more source

UBR5: A New Player in Protein Quality Control for Skeletal Muscle Growth and Remodeling. [PDF]

Exerc Sport Sci Rev
Hughes DC, Bodine SC.
europepmc   +1 more source

A role for the C2 domain of the ubiquitin-protein ligase Nedd4 [PDF]

, 2000
Pamela Plant
openalex  

The HECT ubiquitin‐protein ligase (UPL) family in Arabidopsis: UPL3 has a specific role in trichome development [PDF]

, 2003
Brian P. Downes, Robert M. Stupar, Derek J. Gingerich, Richard D. Vierstra   +3 more
openalex   +1 more source

The Crosstalk Between CRL5 and APC/C E3 Ligases Regulates Metastasis and Chemosensitivity of Cancer Cells

Advanced Science, EarlyView.
This study uncovers a previously unknown crosstalk between two major ubiquitin ligases, CRL5 and APC/C. The authors identify APC11 as a binding partner of CUL5, showing that their interaction regulates neddylation, substrate stability, and mitotic progression.
Danrui Cui, Ruirui Qu, Tianqi Li, Linchen Wang, Xiaoyu Chen, Shengpeng Shao, Xue Liang, Jun Xu, Yi Sun, Xiufang Xiong, Yongchao Zhao   +10 more
wiley   +1 more source

The Ubiquitin-Proteasome System in Hepatitis B Virus Infection and Hepatocarcinogenesis: Viral Manipulation and Therapeutic Targets. [PDF]

J Microbiol Biotechnol
Han J, Kim KH, Seo SU.
europepmc   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source

The enigma of the RING-UIM E3 ligases: its transformative impact on cancer research. [PDF]

J Transl Med
Wang Y, Zhao Y, Xin Q, Zhang J.
europepmc   +1 more source

A ubiquitin-protein ligase (E3) mutation of Saccharomyces cerevisiae suppressed by co-overexpression of two ubiquitin-specific processing proteases.

, 1996
Tosaku Kanda
openalex   +2 more sources

Prognostic value of the ubiquitin ligase carboxyl terminus of the Hsc70‐interacting protein in postmenopausal breast cancer [PDF]

, 2016
Sasagu Kurozumi, Yuri Yamaguchi, Shinichi Hayashi, Hiromi Hiyoshi, Tetsuji Suda, Tatsuyuki Gohno, Hiroshi Matsumoto, Hiroyuki Takei, Jun Horiguchi, Izumi Takeyoshi, Tetsunari Oyama, Masafumi Kurosumi   +11 more
openalex   +1 more source