Results 151 to 160 of about 33,989 (317)

The role of ubiquitin ligases in the control of organ specific autoimmunity [PDF]

open access: yes, 2012
Diabetes mellitus is characterized by chronic hyperglycemia caused by a deficiency in insulin action, insulin secretion or both. Type 1 diabetes is classified as the destruction of beta cells leading to a deficiency in insulin production.
Hoyne, Gerard F
core   +2 more sources

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

open access: yesAdvanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang   +10 more
wiley   +1 more source

GbSER02 Interacts With GhVOZ1 to Promote Fiber Elongation by Modulating Gibberellin Synthesis in Cotton

open access: yesAdvanced Science, EarlyView.
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia   +12 more
wiley   +1 more source

Degradation of Ornithine Decarboxylase in Reticulocyte Lysate Is ATP-dependent but Ubiquitin-independent

open access: hybrid, 1989
Z. Bercovich   +3 more
openalex   +1 more source

Immunogold localisation of ubiquitin‐protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils [PDF]

open access: bronze, 1991
Lajos László   +6 more
openalex   +1 more source

Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

open access: yesAdvanced Science, EarlyView.
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang   +13 more
wiley   +1 more source

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