Results 271 to 280 of about 117,949 (359)

Ubiquitin Immunostaining of Concentric Lamellar Bodies in Axon Terminals and Preterminal Axons in Cerebellar and Vestibular Nuclei of Groggy Mutant Rat

, 1994
Ikuo Takeuchi, Yoshiko Takeuchi, Eiko Aoki   +2 more
openalex   +2 more sources

Cytokinin Growth Responses in Arabidopsis Involve the 26S Proteasome Subunit RPN12 Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010381.

The Plant Cell Online, 2002
Jan A. Smalle, J. Kurepa, Peizhen Yang, E. Babiychuk, S. Kushnir, Adam M. Durski, R. Vierstra   +6 more
semanticscholar   +1 more source

Novel <i>USP18</i> mutations lead to severe interferonopathy responsive to JAK inhibitor. [PDF]

Front Immunol
Sun X, Li M, Dou Y, Wang Q, Lai J, Zhu J, Zhou Q, Yu X.   +7 more
europepmc   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

Advanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye, Anning Zhao, Xia Li, Yanqing Hao, Dong Huang, Jianmin Chen, Tiantian Li, Yangyang Dai, Wenchao Sun, Lie Ma, Songying Zhang, Liaobing Xin   +11 more
wiley   +1 more source

The structural basis for deubiquitination by the fingerless USP-type effector TssM. [PDF]

Life Sci Alliance
Hermanns T, Uthoff M, Baumann U, Hofmann K.   +3 more
europepmc   +1 more source

Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1

Advanced Science, EarlyView.
TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji, Jie Wang, Yi Tu, Shan Zhang, Yong‐Sheng Wei, Yan He, Bin Zhang, Qing‐Qing Zhao, Hao‐Min Hu, Yu Liu   +9 more
wiley   +1 more source

p.Phe508del-CFTR Trafficking: A Protein Quality Control Perspective Through UPR, UPS, and Autophagy. [PDF]

Int J Mol Sci
Trouvé P, Férec C.
europepmc   +1 more source

Redox Cascade in Chicken Skeletal Muscle: SELENOT Suppression in Selenium Deficiency Triggers Disulfidptosis via mtROS‐NADPH Dysregulation

Advanced Science, EarlyView.
Se deficiency downregulates SELENOT, disrupting mitochondrial function and elevating mtROS to induce glucose metabolic reprogramming, NADPH depletion, cysteine accumulation, and disulfidptosis‐mediated actin cytoskeleton collapse in chicken skeletal muscle.
Huanyi Liu, Hao Wu, Ziyu Zhang, Shiwen Xu, Cong Zhou, Tong Xu   +5 more
wiley   +1 more source

Multiple forms of the 20 S multicatalytic and the 26 S ubiquitin/ATP-dependent proteases from rabbit reticulocyte lysate.

, 1992
Laura Hoffman, G Pratt, Martin Rechsteiner   +2 more
openalex   +1 more source

MYLIP attenuates hypoxia tolerance by inducing K27-linked polyubiquitination and subsequent proteasomal degradation of HIF-α. [PDF]

Commun Biol
Li J, Li Z, Li X, Li Z, Song Y, Yuan L, Wang Y, Yan R, Lai F, Wang J, Xiao W.   +10 more
europepmc   +1 more source