Results 91 to 100 of about 119,003 (273)
VIEW, EarlyView.We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani +12 more
wiley +1 more source
TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
Insect Science, EarlyView.RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Bad Designs by Good Talkers: Chatbots Failing to Architect Audio Encoders for Image Synthesis
IEEE AccessOn one hand, recent advances in chatbots have led to a rising popularity in using these models for coding tasks. On the other hand, modern generative image models primarily rely on text encoders to translate semantic concepts into visual representations,
Jorge E. Leon +2 more
doaj +1 more source
Creation of bioactive non‐natural flavonoids via combinatorial prenylation–glycosylation cascades
mLife, EarlyView.
Hongjiao Zhang +3 more
wiley +1 more source
The FEBS Journal, EarlyView.Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola +11 more
wiley +1 more source
[UDP-glucuronosyltransferase].
Nihon eiseigaku zasshi. Japanese journal of hygiene, 2002 UDP-glucuronosyltransferases (UGTs) represent a family of enzymes that glucuronidate many internal substances and drugs. This family acts as a drug metabolism phase II reactor in the liver and comprises one of the major protective mechanisms from toxic chemical substances. UGTs have two subfamilies; UGT1 and UGT2.
Yoshihiro, Maruo, Hiroshi, Sato
openaire +1 more source
Journal of Integrative Plant Biology, EarlyView.High‐quality genomes of four wild raspberry species, analysis of their genetic relationships, identification of centromeres as markers for tracing their hybrid origins, exploration of fruit quality regulation, and discovery of a gene blocking anthocyanin transport and thus causing yellow fruits provides valuable resources for raspberry breeding ...
Ticao Zhang +11 more
wiley +1 more source
Journal of Integrative Plant Biology, EarlyView.Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu +9 more
wiley +1 more source
Targeted metabolomic evaluation of peripheral blood mononucleated cells from patients with PMM2-CDG
Scientific ReportsPhosphomannomutase-2 (PMM2) deficiency represents the most common congenital disorder of glycosylation (CDG). Currently, little is known about cell metabolic alterations occurring in these patients.
Renata Mangione +20 more
doaj +1 more source