Results 161 to 170 of about 30,370 (271)

Geochemical and Isotopic Constraints on Long‐Lived Source Enrichment and Mantle Evolution in Paleoproterozoic Cratonic Lamprophyres

open access: yesGeochemistry, Geophysics, Geosystems, Volume 27, Issue 6, June 2026.
Abstract The cratonic lithospheric mantle records complex metasomatic processes and is frequently tapped by alkaline magmatism, offering a unique opportunity to trace the progressive evolution of the mantle. In the present contribution, we investigate a newly identified calc‐alkaline lamprophyre field from the Neoarchean Jonnagiri Schist Belt, Eastern ...
Sourav Naskar   +6 more
wiley   +1 more source

Self‐Supervised Radar Nowcasting of Typhoon Cloud Evolution

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 3, June 2026.
Abstract Self‐supervised learning (SSL) provides an innovative paradigm for pretraining without involving any new data or labels. However, its potential has not yet been evaluated in the field of typhoon raincloud nowcasting. Therefore, we explore two different SSL approaches: autoencoder (AE) and masked autoencoder (MAE).
Hongyi Yao   +7 more
wiley   +1 more source

Humanized Antibodies Targeting Ectodomains of IL‐6R and GP130 Suppress IL‐6/STAT3 Signalling and Tumour Growth in Breast Cancer Models

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Interleukin‐6 (IL‐6) signalling is a key driver of breast cancer progression, activating pro‐survival, pro‐inflammatory and metastatic programs through its receptors, IL‐6R and GP130. Elevated IL‐6 levels correlate with poor prognosis in breast cancer patients and persistent IL‐6/STAT3 activation promotes tumour proliferation, metastasis ...
Satyajit Dey Pereira   +10 more
wiley   +1 more source

Effects of Lysine Deacetylation Inhibition Alone or in Combination With Arimoclomol on TDP‐43 Proteinopathy

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
TDP‐43 pathology is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Peptidyl‐prolyl cis–trans isomerase A (PPIA), a foldase and chaperone protein, modulates TDP‐43 function in an acetylation‐dependent manner. Here, we show that inhibition of lysine deacetylation with vorinostat (SAHA) increases PPIA acetylation and ...
Serena Scozzari   +10 more
wiley   +1 more source

UGC in a selected hotel in Prague

open access: yes
This bachelor's thesis deals with the concept of user-generated content (UGC) in a selected hotel in Prague. The primary purpose of this work is to analyze the content published online related to the hotel and create a manual that could be incorporated ...
Pham, Thao Huong
core  

HLA‐B*44 Alleles and HLA‐DQA1*03:01 as Genetic Risk Factors for Drug‐Induced Liver Injury due to Fluoroquinolones

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Fluoroquinolone exposure can give rise to drug‐induced liver injury. Genetic risk factors for this form of liver injury are poorly understood but some evidence suggests that HLA genes contribute. This study aimed to characterise HLA risk factors for fluoroquinolone‐induced liver injury in a European population. Methods From
Paola Nicoletti   +10 more
wiley   +1 more source

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