Results 61 to 70 of about 65,761 (163)

Doebner-type pyrazolopyridine carboxylic acids in an Ugi four-component reaction [PDF]

open access: yes, 2019
Substituted 1H-pyrazolo[3,4-b]pyridine-4- and 1H-pyrazolo[3,4-b]pyridine-6-carboxamides have been synthetized through a Doebner–Ugi multicomponent reaction sequence in a convergent and versatile manner using diversity generation strategies: combination ...
Brazhko, O. A.   +11 more
core  

Practical access to planar chiral 1,2-(α-Ketotetramethylene)- ferrocene by non-enzymatic kinetic resolution and conclusive confirmation of its absolute configuration [PDF]

open access: yes, 2015
The asymmetric transfer hydrogenation (ATH) of racemic 1,2-(α-ketotetramethylene)ferrocene using the [N-(tosyl)-1,2-diphenylethylendiamine]ruthenium(II) complex [TsDPEN-Ru(II)] as catalyst takes place with a high level of kinetic resolution to deliver ...
Akiyama   +98 more
core   +1 more source

Synthesis of Functionalized Spiro-Heterocycles by Sequential Multicomponent Reaction/Metal Catalyzed Carbocylizations from Simple β-Ketoesters and Amides

open access: yes, 2007
International audienceA new strategy from simple cyclic β-ketoesters or amides involving a selective three-component reaction and a ring closing metathesis or a palladium catalyzed carbocyclization in a sequential fashion to access spiro-heterocycles is ...
Habib-Zahmani, Hadjira   +2 more
core   +4 more sources

Meglumine catalyzed one-pot green synthesis of novel 4,7-dihydro-1H-pyrazolo3,4-bpyridin-6-amines [PDF]

open access: yes, 2017
Meglumine efficiently catalyzes the one-pot, five-component reaction of hydrazine, ethyl acetoacetate, aryl aldehydes, substituted phenylacetonitriles and ammonium acetate in ethanol at room temperature to afford novel 4,7-dihydro-1H-pyrazolo3,4-bpyridin-
Govindaraju, S.   +3 more
core   +1 more source

Pentazole and Ammonium Pentazolate: Crystalline Hydro-Nitrogens at High Pressure

open access: yes, 2017
Two new crystalline compounds, pentazole (N_{5}H) and ammonium pentazolate (NH_{4})(N_{5}), both featuring cyclo-{\rm N_{5}^{-}} are discovered using first principles evolutionary search of the nitrogen-rich portion of the hydro-nitrogen binary phase ...
Oleynik, Ivan I., Steele, Brad A.
core   +4 more sources

Recent Advances in Biocatalytic Promiscuity: Hydrolase-Catalyzed Reactions for Nonconventional Transformations [PDF]

open access: yes, 2015
Financial support from the Spanish Ministerio de Economía y Competitividad (CTQ2013-44153-P) is grateful acknowledged. M.L.-I.
Gotor Fernández, Vicente   +1 more
core   +2 more sources

A structurally conserved motif in γ-herpesvirus uracil-DNA glycosylases elicits duplex nucleotide-flipping [PDF]

open access: yes, 2018
Efficient γ-herpesvirus lytic phase replication requires a virally encoded UNG-type uracil-DNA glycosylase as a structural element of the viral replisome.
Bagneris, Claire   +5 more
core   +2 more sources

Enantiopure Ferrocene-Based Planar-Chiral Iridacycles:Stereospecific Control of Iridium-Centred Chirality [PDF]

open access: yes, 2016
Reaction of [IrCp*Cl-2](2) with ferrocenylimines (Fc=NAr, Ar=Ph, p-MeOC6H4) results in ferrocene C-H activation and the diastereoselective synthesis of half-sandwich iridacycles of relative configuration S-p*,R-Ir*.
Albrecht   +78 more
core   +1 more source

Catalyst optimisation for asymmetric synthesis by ligand chirality element addition - a perspective on stereochemical cooperativity [PDF]

open access: yes, 2017
The concept of matched and mismatched stereochemical pairings has been utilised extensively in organic synthesis, with the cooperativity resulting from the former enabling many reactions to proceed with high stereoselectivity.
Arthurs, Ross   +1 more
core   +1 more source

Synthesis of dihydrophenanthridines by a sequence of Ugi-4CR and palladium-catalyzed intramolecular C-H functionalization

open access: yesBeilstein Journal of Organic Chemistry, 2008
Background Small polyfunctionalized heterocyclic compounds play important roles in the drug discovery process and in the isolation and structural identification of biological macromolecules.
Florence Bonnaterre   +2 more
semanticscholar   +1 more source

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