Results 41 to 50 of about 23,282 (131)
Recent Applications of Sulfonium Salts in Synthesis and Catalysis
Chemistry – A European Journal, Volume 30, Issue 70, December 13, 2024.This review summarizes the recent developments on the synthetic applications of sulfonium salts with an emphasis on the description of the operating mechanistic pathways. Abstract The use of sulfonium salts in organic synthesis has experienced a dramatic increase during the last years that can arguably be attributed to three main factors; the ...
Sven Timmann, Zeyu Feng, Manuel Alcarazo
wiley +1 more source
Isonitrile Photochemistry: A Functional Group Class Coming in from the Cold
Chemistry – A European Journal, Volume 30, Issue 64, November 15, 2024.Isonitriles, often neglected for their unpleasant smell, have fascinated many generations of chemists thanks to unique reactivity modes. The present concept article, by retracing the seeds of isonitrile photochemistry, points out the hidden opportunities offered by visible light photo(redox) catalysis to promote key advancements in the field.
Mariateresa Giustiniano
wiley +1 more source
Here we report an organocatalytic double Ugi reaction combining the enantioselective process and ee enhancement in a single operation to afford the chiral Ugi products with very high ee values.
Tong, Shuo +3 more
core +1 more source
Catalytic Three-Component Ugi Reaction
, 2008 Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Different α‐amino amides are formed in good yields from aldehydes, primary amines, and isocyanides in the presence of phenyl phosphinic acid as the catalyst.
List, B., Pan, S.
core +1 more source
Protein-Templated Hit Identification through an Ugi Four-Component Reaction. [PDF]
, 2020 Kinetic target-guided synthesis represents an efficient hit-identification strategy, in which the protein assembles its own inhibitors from a pool of complementary building blocks via an irreversible reaction. Herein, we pioneered an in situ Ugi reaction
Jumde, Varsha R +29 more
core +1 more source
‐heterocycles Using the Ugi Four‐Center Three‐Component Reaction
, 2019 Ugi four-center three-component reaction (U-4 C-3CR) as actually an important development of the well-known Ugi four-component reaction (U-4CR). In U-4 C-3CR, one of the components is bifunctional, reducing the components of U-4CR to three components ...
M Heravi; Majid +3 more
core +1 more source
Conditions have been developed for the multicomponent synthesis of di- and tetrapeptide based on the unique reactivity of alpha -isocyanoacetic acids (including its alpha -substituted derivs.) by an Ugi four-component, five-center reaction. Simply mixing
Dekhane, Mouloud +2 more
core +1 more source
Model Studies on the First Enzyme-Catalyzed Ugi Reaction
, 2016 Multicomponent reactions are powerful tools for organic chemistry, and among them, the Ugi reaction provides remarkable improvement in many fields of organic chemistry such us combinatorial chemistry, medicinal chemistry, and peptide chemistry.
Stanisław Berłożecki (1997758) +3 more
core +1 more source
SYNTHESIS OF AZULENE AMIDE DERIVATIVES BY SOLVENT-FREE UGI REACTION
, 2014 A simple and eco-friendly synthesis of azulene amide derivatives has achieved via solvent-free Ugi reaction. We found that efficient solvent-free reactions required the formation of a liquid phase throughout the course of the reactions.
熊倉 健太
core
Diastereoselective Ugi reaction for the synthesis of unnatural amino esters
, 2012 Multicomponent Reactions (MCR) are useful reactions to obtain complex products by the simple mixture of 3 or more reactants. The classic Ugi reaction (4-UCR) involves a mixture of an amine, aldehyde, isocyanide and a carboxylic acid, giving peptoides as ...
Carlos Kleber Z. Andrade +4 more
core +1 more source