Results 61 to 70 of about 23,282 (131)

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

Reaction of isonitriles with 3-(arylamino)isobenzofuran-1(3H)-ones in the presence of a catalytic amount of an octahydro (R)-binol-derived chiral phosphoric acid afforded 3-oxo-2-arylisoindoline-1-carboxamides in high yields with good to high ...
Huang, Zhi-Tang, Wang, De-Xian, Ao, Yu-Fei, Wang, Mei-Xiang, Zhu, Jieping, Zhang, Yun   +5 more
core   +1 more source

Correction: An intramolecular hydrogen bond-promoted "green" Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity. [PDF]

RSC Adv, 2023
Li J, Huang JH, Wang JY, Xu ZG, Chen ZZ, Lei J.   +5 more
europepmc   +1 more source

Optimization of a Novel Oxy-Michael Ugi-Smiles Reaction

, 2017
Synthesis of complex, biologically active molecules is critical for the discovery and development of potential pharmaceutical agents. Multicomponent coupling reactions (MCRs) are “one-pot reactions” that combine three or more compounds simultaneously to ...
Ayres, Robert
core  

Stabilization of Cyclic β‑Hairpins by Ugi-Reaction-Derived N‑Alkylated Peptides: The Quest for Functionalized β‑Turns

, 2019
A solid-phase approach including on-resin Ugi reactions was developed for the construction of β-hairpins. Various N-alkylated dipeptide fragments proved capable of aligning antiparallel β-sheets in a macrocyclic scaffold, thus serving as β-hairpin ...
Ludger A. Wessjohann, Aldrin V. Vasco (7340933), Daniel G. Rivera (1392718), Manuel G. Ricardo, Ludger A. Wessjohann (578796), Aldrin V. Vasco, Daniel G. Rivera, Manuel G. Ricardo (7340930)   +7 more
core   +1 more source

UEG Week 2024 Moderated Posters

United European Gastroenterology Journal, Volume 12, Issue S8, Page 201-664, October 2024.
wiley   +1 more source

UEG Week 2024 Poster Presentations

United European Gastroenterology Journal, Volume 12, Issue S8, Page 665-1360, October 2024.
wiley   +1 more source

Rapid access to oxindoles by the combined use of an Ugi four-component reaction and a microwave-assisted intramolecular Buchwald-Hartwig amidation reaction

A two-step sequence involving an Ugi four-component reaction (Ugi-4CR) and a palladium-catalyzed intramol. amidation of aryl iodide has been developed for rapid access to functionalized oxindoles, e.g., I.
Bois-Choussy, Michele, Zhu, Jieping, Bonnaterre, Florence   +2 more
core   +1 more source

Diastereoselective Ugi Reaction Without Chiral Amines: The Synthesis of Chiral Pyrroloketopiperazines

, 2007
The three-component Ugi reaction with chiral 2-(2-formyl-1H-pyrrol-1-yl)acetic acids prepared from natural l-aminoacids was investigated. The reaction opens a new route to chiral substituted pyrroloketopiperazines.
Reznichenko, Alexander L.; id_orcid, Balenkova, Elizabeth S., Valentine G. Nenajdenko, Elizabeth S. Balenkova, Alexander L. Reznichenko, Nenajdenko, Valentine G.   +5 more
core   +1 more source

An intramolecular hydrogen bond-promoted "green" Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity. [PDF]

RSC Adv, 2022
Li J, Huang JH, Wang JY, Xu ZG, Chen ZZ, Lei J.   +5 more
europepmc   +1 more source

Ugi Four-Component Reactions Using Alternative Reactants. [PDF]

Molecules, 2023
Hooshmand SE, Zhang W.
europepmc   +1 more source