Results 61 to 70 of about 2,740,315 (129)

Optimization of a Novel Oxy-Michael Ugi-Smiles Reaction

, 2017
Synthesis of complex, biologically active molecules is critical for the discovery and development of potential pharmaceutical agents. Multicomponent coupling reactions (MCRs) are “one-pot reactions” that combine three or more compounds simultaneously to ...
Ayres, Robert
core  

Rapid synthesis of cyclopeptide alkaloid-like para-cyclophanes by combined use of Ugi-4CR and intramolecular SNAr reaction

The title cyclophanes, such as I, were prepd. via a Ugi-4CR four component reaction and subsequent macrocyclization of the resulting amides using intramol. SNAr reactions.
Cristau, Pierre, Vors, Jean-Pierre, Zhu, Jieping   +2 more
core   +1 more source

FACILE SYNTHESIS OF AZULENE AMIDE DERIVATIVES WITH HETEROCYCLIC RESIDUES USING UGI REACTION [PDF]

, 2008
Many synthetic research reports on heterocyclic compounds by Ugi reaction have appeared in recent years. Starting from 3-isocyanoguaiazulene (3-isocyano-7-isopropyl-1,4-dimethylazulene), there were performed our synthetic studies by Ugi reaction on a ...
深澤 甲
core  

Synthesis of Multifunctional Polymers through the Ugi Reaction for Protein Conjugation

, 2016
The Ugi reaction has been utilized as a multicomponent click reaction to efficiently synthesize a series of multifunctional PEGylation agents, and those PEG derivatives were successfully conjugated on a protein surface to generate corresponding ...
Yuan Zhao (336512), Yen Wei (1396648), Lei Tao (422964), Bin Yang (103252), Shiqi Wang (163773), Changkui Fu (1483129), Yaling Zhang (1687540)   +6 more
core   +1 more source

Chiral Phosphoric Acid Catalyzed Asymmetric Ugi Reaction by Dynamic Kinetic Resolution of the Primary Multicomponent Adduct

Reaction of isonitriles with 3-(arylamino)isobenzofuran-1(3H)-ones in the presence of a catalytic amount of an octahydro (R)-binol-derived chiral phosphoric acid afforded 3-oxo-2-arylisoindoline-1-carboxamides in high yields with good to high ...
Huang, Zhi-Tang, Wang, De-Xian, Ao, Yu-Fei, Wang, Mei-Xiang, Zhu, Jieping, Zhang, Yun   +5 more
core   +1 more source

Correction: An intramolecular hydrogen bond-promoted "green" Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity. [PDF]

RSC Adv, 2023
Li J, Huang JH, Wang JY, Xu ZG, Chen ZZ, Lei J.   +5 more
europepmc   +1 more source

Rapid access to oxindoles by the combined use of an Ugi four-component reaction and a microwave-assisted intramolecular Buchwald-Hartwig amidation reaction

A two-step sequence involving an Ugi four-component reaction (Ugi-4CR) and a palladium-catalyzed intramol. amidation of aryl iodide has been developed for rapid access to functionalized oxindoles, e.g., I.
Bois-Choussy, Michele, Zhu, Jieping, Bonnaterre, Florence   +2 more
core   +1 more source

An intramolecular hydrogen bond-promoted "green" Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity. [PDF]

RSC Adv, 2022
Li J, Huang JH, Wang JY, Xu ZG, Chen ZZ, Lei J.   +5 more
europepmc   +1 more source

Ugi Four-Component Reactions Using Alternative Reactants. [PDF]

Molecules, 2023
Hooshmand SE, Zhang W.
europepmc   +1 more source

Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach. [PDF]

Molecules, 2022
P R, Thomas J, Dehaen W, John J.
europepmc   +1 more source