Results 21 to 30 of about 2,093 (93)

Experimental and theoretical studies on the effect of the oxo group in 1,4-benzodiazepines [PDF]

, 2014
Two families of regioisomeric 1,4-benzodiazepines, 4-benzyl-3H-benzo[e][1,4]diazepin-5-ones and 4-benzoyl-4,5-dihydro-3H-benzo[e][1,4]diazepines, have been synthesized through a similar Ugi/reduction cyclization sequence. Their conformation and stability
Cordero Tejedor, Nicolás A., García Valverde, María, González Ortega, Alfonso ., Pertejo Fernández, Pablo, Peña Calleja, Pablo, Torroba Pérez, Tomás   +5 more
core   +1 more source

Multicomponent synthesis of 4,4-dimethyl sterol analogues and their effect on eukaryotic cells [PDF]

, 2014
Most sterols, such as cholesterol and ergosterol, become functional only after the removal of the two methyl groups at C-4 from their biosynthetic precursors.
Alonso, Fernando, Barquero, Andrea Alejandra, Cabrera, Gabriela Myriam, Cirigliano, Adriana Monica, Davola, Maria Eugenia, Garcia Liñares, Guadalupe Eugenia, Labriola, Carlos Alberto, Ramirez, Javier Alberto   +7 more
core   +1 more source

Design e síntese de nanopartículas magnéticas funcionalizadas com peptóides para a remoção de cromo de resíduos aquosos [PDF]

, 2015
Dissertação (mestrado)–Universidade de Brasília, Faculdade UnB Planaltina, Mestrado em Ciência de Materiais, 2015.No presente trabalho realizou-se a síntese de nanopartículas magnéticas de óxido de ferro que foram funcionalizadas com peptóides.
Costa, Hingrid Lorrane Vieira da
core   +1 more source

7,7′-(1,4-Phenylene)bis(2-benzyl-3-(3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one)

Molbank
The multicomponent synthesis of a novel and highly symmetric polyheterocycle based on the pyrrolo[3,4-b]pyridin-5-one core incorporating the privileged tetrahydroisoquinoline moiety is described.
Roberto E. Blanco-Carapia, Alejandro Islas-Jácome, Eduardo González-Zamora   +2 more
doaj   +1 more source

Stereospecific synthesis of syn-alpha-oximinoamides by a three-component reaction of isocyanides, syn-chlorooximes, and carboxylic acids [PDF]

, 2011
A stereospecific multicomponent reaction among isocyanides, nitrile N-oxides and carboxylic acids provides an efficient synthesis of biologically relevant syn \u3b1 ...
Galli, Simona, Mossetti, Riccardo, Pirali, Tracey, Tron, Gian Cesare   +3 more
core   +1 more source

Silver(I) triflate-catalyzed protocol for the post-ugi synthesis of spiroindolines

, 2019
A silver(I) triflate-catalyzed protocol for the post-Ugi synthesis of tetracyclic spiroindolines has been developed. The protocol worked best for indole-3-carbaldehyde-derived Ugi adducts obtained using anilines and 3-aryl propiolic acids.
Hasan, Muhammad, Pereshivko, Olga P., Peshkov, Anatoly A., Peshkov, Vsevolod A., Van der Eycken, Erik V., Van Hecke, Kristof, Zaman, Manzoor   +6 more
core   +1 more source

Genome-editing based engineering of CESA3 dual cellulose-inhibitor resistant plants [PDF]

, 2019
The rapid appearance of herbicide-resistant weeds combined with a lack of novel herbicides being brought to market reduces crop production, thereby threatening food security worldwide.
D'Haeyer, Sam, De Veylder, Lieven, Decaestecker, Ward, Hu, Zhubing, Höfer, René, Jacobs, Thomas, Karimi, Mansour, Rombaut, Debbie, Vercauteren, Ilse, Xing, Aiming, Zhang, Teng   +10 more
core   +1 more source

A modular, one-pot, four-component synthesis of polysubstituted 1,3-oxazolidines [PDF]

, 2005
4 pages, 1 figure, 1 table, 1 scheme.-- PMID: 15675866 [PubMed].-- Printed version published Feb 4, 2005.Supporting information available: Spectroscopic and analytical data for compounds 3c-j.-- Available at: http://pubs.acs.org/doi/suppl/10.1021 ...
García-Tellado, Fernando, González-Cruz, David, Marrero-Tellado, José Juan, Santos-Expósito, Alicia, Tejedor, David   +4 more
core   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

NMR‐Based Structural Analysis of Highly Substituted Pyridines From Kondrat'eva Aza‐Diels–Alder Cycloadditions

Magnetic Resonance in Chemistry, Volume 64, Issue 3, Page 324-332, March 2026.
We report the results from a kinetic and mechanistic investigation of an inverse‐electron‐demand Diels–Alder (IEDDA) cycloaddition involving an oxazole‐type diene synthesized via an Ugi–Zhu multicomponent reaction (UZ‐3CR). ABSTRACT Pyridines are a crucial class of heterocycles with widespread applications in natural products, pharmaceuticals, and ...
Galdina V. Suárez‐Moreno, Francisco Méndez, Atilano Gutierrez‐Carrillo, Mónica A. Rincón‐Guevara, Yoarhy A. Amador‐Sánchez, Alejandro Islas‐Jácome, Eduardo González‐Zamora   +6 more
wiley   +1 more source