Results 21 to 30 of about 2,740,315 (129)

Novel postmodifications of the Ugi reaction [PDF]

open access: yes, 2016
In dieser Arbeit wurden neuartige Postmodifikationen von Produkten der Ugi-4CR untersucht. Ihre Möglichkeiten und Grenzen wurden durch das Permutieren der notwendigen funktionellen Gruppen um das Ugi-Grundgerüst herum und durch Synthese von ...
Welsch, Sebastian
core   +1 more source

Ugi four-component reaction of alcohols: stoichiometric and catalytic oxidation/MCR sequences.

open access: yes, 2013
International audienceA new, simple, and efficient procedure for the one-pot Ugi four-component reaction of alcohols instead of aldehydes is described. Using a stoichiometric amount of IBX or only 1-2% of sodium 2-iodobenzenesulfonate in the presence of ...
Drouet, Fleur   +2 more
core   +2 more sources

Direct synthesis of the arylboronic acid analogues of phenylglycine via microwave-assisted four-component Ugi reaction

open access: yes, 2014
A four-component Ugi reaction (Ugi-4CR) utilizing formylphenyl boronic acids under mild condition was developed for the synthesis of arylboronic acid analogs.
Lian, Ru-Ching; Lin, Meng-Hsuan; Liao, Pin-Hsuan; Fu, Jia-Jie; Wu, Meng-Ju; Wu, Yang-Chang; Chang, Fang-Rong; Wu, Chin-Chung; Pan, Po-Shen   +1 more
core   +1 more source

Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction? [PDF]

open access: yes, 2022
This year represents the 100th anniversary of the discovery of the Passerini three-component reaction. The related Ugi four-compound reaction was discovered 37 years after the Passerini reaction.
Dömling, Alexander, Alexander Dömling
core   +2 more sources

7,7′-(1,4-Phenylene)bis(2-benzyl-3-(3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methoxybenzyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one)

open access: yesMolbank
The multicomponent synthesis of a novel and highly symmetric polyheterocycle based on the pyrrolo[3,4-b]pyridin-5-one core incorporating the privileged tetrahydroisoquinoline moiety is described.
Roberto E. Blanco-Carapia   +2 more
doaj   +1 more source

Ugi coupling reaction.

open access: yes, 2016
The Ugi coupling reaction involves the combination of isocyanide (a), aldehyde (b), amine (c) and carboxylic acid (d) components in a single reaction step to give an α-aminoacyl amide product, as exemplified above for the preparation of AZ126.
Darren S. Heeke (3220149)   +13 more
core   +1 more source

Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics [PDF]

open access: yes, 2017
A general strategy is introduced for the efficient synthetic access of disulfide linked artificial macrocycles via a Ugi four-component reaction (U4CR) followed by oxidative cyclization.
Vishwanatha, Thimmalapura M   +5 more
core   +2 more sources

The Ugi reaction in polymer chemistry: syntheses, applications and perspectives

open access: yes, 2015
The Ugi reaction, one of the most famous multicomponent reactions, has recently been introduced into polymer chemistry as a novel, efficient and useful tool to prepare multifunctional polymers.
Wei, Yen   +4 more
core   +1 more source

Synthesis of Oxazolyl‐Piperidines Bearing a Quaternary Stereocenter Through a Multicomponent Reaction Involving α‐Isocyanoacetates and Piperidones

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.
Straightforward access to oxazole‐containing piperidines through a multicomponent reaction from α‐isocyanoacetates is described. By expanding the reactivity of these a‐isocyanoacetates from aldehydes to ketones, this process efficiently delivers oxazolyl‐piperidines bearing a quaternary stereocenter as valuable scaffolds relevant to drug discovery. The
Roshan Chandrakant Kajare   +3 more
wiley   +1 more source

Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings [PDF]

open access: yes, 2017
An Ugi multicomponent reaction based two-step strategy was applied to generate medium-sized rings. In the first linear expansion phase, a series of diamines reacted with cyclic anhydrides to produce different lengths of terminal synthetic amino acids as ...
Rossetti A.   +6 more
core   +4 more sources

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