Results 141 to 150 of about 49,542 (253)

SPE-UHPLC-MS/MS Method for Simultaneous Quantification of 50 Pesticide Biomarkers Across Nine Current-Use Chemical Classes in Human Urine. [PDF]

J Xenobiot
Jagani R, Chovatiya J, Patel H, Teraiya S, Pulivarthi D, Andra SS.   +5 more
europepmc   +1 more source

Detection of Testosterone Esters in Urine: Evidence of Trace‐Level Detectability in Doping Control Samples

Drug Testing and Analysis, EarlyView.
An ultrasensitive LC‐MS/MS method for detecting testosterone esters (T‐esters) in urine at sub–pg/mL levels is presented. This approach, employing Girard P derivatization, provides the first evidence of T‐esters' trace‐level detectability in human urine.
Daniel Pecher, Guro Forsdahl, Biljana Stojanovic, Günter Gmeiner   +3 more
wiley   +1 more source

UHPLC-MS/MS for Antipsychotic Drug Monitoring: A Systematic Review of Clinical and Analytical Performance. [PDF]

J Clin Med
Băcilă CI, Macavei BM, Cornea M, Vintilă BI, Lomnășan A, Anghel CE, Grama AM, Dobre CE, Ichim CM, Cioca G.   +9 more
europepmc   +1 more source

Chemically Modular, Nonfluorinated Polymer Adsorbents for Capturing Per‐ and Polyfluoroalkyl Substances (PFAS)

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Nonfluorinated polymer networks for PFAS adsorption are synthesized using active ester click chemistry. Incorporating Lewis base ligands along with hydrophilic and hydrophobic co‐monomers leads to high PFOA binding efficiency. Ligand basicity and pH are found to play an important role in PFOA sorption.
Lakshay K. Dhamania, Joshua D. Moon
wiley   +1 more source

Development and Validation of a Rapid and Simple UHPLC-MS/MS Method for the Determination of Colchicine in Human Plasma. [PDF]

Biomed Chromatogr
Žideková N, Pršo K, Pršo M, Jeseňák M, Farsa O, Kertys M.   +5 more
europepmc   +1 more source

A Novel HILIC‐UPLC‐DAD‐MS/MS Method for the Analysis of Mycosporine‐Like Amino Acids and Their Quantification in Diverse Algae

ELECTROPHORESIS, EarlyView.
The separation of selected mycosporine‐like amino acids and two biosynthetic precursors, in total 13 compounds, by HILIC‐UPLC is described for the first time. With an analysis time of only 5 min, it surpasses all currently known methods for analysis of these promising natural products.
Armin Oberosler, Anastasiia Fedorova, Ignacio Zegri, Fabian Hammerle, Michael Zwerger, Thomas Werner, Markus Ganzera   +6 more
wiley   +1 more source

Optimized iCIEF Fractionation Enables Deep Profiling of Antibody Drug Conjugate Charge Heterogeneity

ELECTROPHORESIS, EarlyView.
This study developed and optimized an iCIEF fractionation method to characterize ADC charge variants. The optimized approach enabled stable separation, identification of major PTMs, and drug‐load distributions across light and heavy chains. ABSTRACT Antibody drug conjugates (ADCs) are a novel class of therapeutic drugs that combine selectivity of an ...
Eunju Jang, Qunying Zhang, Paul M. Thomas   +2 more
wiley   +1 more source

UHPLC-MS/MS Method for the Simultaneous Quantification of 12 Antiretroviral Drugs in Human Plasma Using Dried Sample Spot Devices: Development, Validation, and Stability Evaluation. [PDF]

Pharmaceutics
Soloperto S, Martina E, Palermiti A, Barnini E, Sabbia G, Bianco G, Billi M, Martino C, Manca A, Simiele M, Cusato J, D'Avolio A, De Nicolò A.   +12 more
europepmc   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Comprehensive metabolites characterization of Alpinia katsumadai seeds via a multiplex approach of UHPLC-MS/MS and GC-MS techniques. [PDF]

Sci Rep
Ali NB, Hussein ME, Farag MA.
europepmc   +1 more source