Results 1 to 10 of about 61,720 (161)

Simultaneous Determination of Structurally Diverse Compounds in Different Fangchi Species by UHPLC-DAD and UHPLC-ESI-MS/MS

Molecules, 2013
Two bisbenzylisoquinoline alkaloids, two morphine alkaloids, one aporphine alkaloid, syringaresinol and aristolochic acid І were selected as marker compounds and simultaneously analyzed using an ultra-high pressure liquid chromatography-diode array ...
Jongki Hong
exaly   +3 more sources

UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis [PDF]

Scientific Reports
The diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen, Annukka Pietikäinen, Tiia Rissanen, Saija Hurme, Elisa Kortela, Mari J. Kanerva, Jarmo Oksi, Jukka Hytönen, Maarit Karonen   +8 more
doaj   +2 more sources

Development and Validation of a UHPLC-MS/MS Method for Ciprofol Detection in Plasma: Application in Clinical Pharmacokinetic Studies [PDF]

Drug Design, Development and Therapy
Jiaxi Zhu,1,2,* Ying Cao,2,* Xingan Zhang,2 Bo Xu2 1The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, 510515, People’s Republic of China; 2Department of Anesthesiology, General Hospital of Southern ...
Zhu J, Cao Y, Zhang X, Xu B
doaj   +2 more sources

A Strategy for Identification and Structural Characterization of Compounds from Plantago asiatica L. by Liquid Chromatography-Mass Spectrometry Combined with Ion Mobility Spectrometry

Molecules, 2022
Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging.
Hongxue Gao, Zhiqiang Liu, Fengrui Song, Junpeng Xing, Zhong Zheng, Shu Liu   +5 more
doaj   +1 more source

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS

Frontiers in Plant Science, 2023
Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Chenghuan Yan, Chenghuan Yan, Yan Huang, Yan Huang, Shuting Zhang, Shuting Zhang, Lei Cui, Lei Cui, Zhenbiao Jiao, Zhenbiao Jiao, Zhaoxin Peng, Xiaozhou Luo, Yun Liu, Zhengming Qiu, Zhengming Qiu   +14 more
doaj   +1 more source

Chronic dietary intake of enniatin B in broiler chickens has low impact on intestinal morphometry and hepatic histology, and shows limited transfer to liver tissue [PDF]

, 2018
The Fusarium mycotoxin enniatin B (ENN B) is a so-called emerging mycotoxin frequently contaminating poultry feed. To investigate the impact of chronic ENN B exposure on animal health, broiler chickens were fed either a diet naturally contaminated with ...
Antonissen, Gunther, Croubels, Siska, Devreese, Mathias, Ducatelle, Richard, Fraeyman, Sophie, Rychlik, Michael   +5 more
core   +8 more sources

Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes

Molecules, 2021
Two new ultra-high performance liquid chromatography (UHPLC) methods for analyzing 21 selected antivirals and their metabolites were optimized, including sample preparation step, LC separation conditions, and tandem mass spectrometry detection.
Luboš Fical, Maria Khalikova, Hana Kočová Vlčková, Ivona Lhotská, Zuzana Hadysová, Ivan Vokřál, Lukáš Červený, František Švec, Lucie Nováková   +8 more
doaj   +1 more source

Recent Developments Toward Integrated Metabolomics Technologies (UHPLC-MS-SPE-NMR and MicroED) for Higher-Throughput Confident Metabolite Identifications

Frontiers in Molecular Biosciences, 2021
Metabolomics has emerged as a powerful discipline to study complex biological systems from a small molecule perspective. The success of metabolomics hinges upon reliable annotations of spectral features obtained from MS and/or NMR. In spite of tremendous
Rajarshi Ghosh, Rajarshi Ghosh, Rajarshi Ghosh, Rajarshi Ghosh, Guanhong Bu, Guanhong Bu, Brent L. Nannenga, Brent L. Nannenga, Lloyd W. Sumner, Lloyd W. Sumner, Lloyd W. Sumner, Lloyd W. Sumner   +11 more
doaj   +1 more source

Chemotaxonomic Markers for the Leaf Buds of Common Finnish Trees and Shrubs: A Rapid UHPLC MS Fingerprinting Tool for Species Identification

Molecules, 2022
In this study, a chemotaxonomic tool was created on the basis of ultra-high-performance liquid chromatography–mass spectrometry (UHPLC–MS) for the identification of 13 common Finnish deciduous trees and shrubs from their leaf bud metabolites.
Marianna Manninen, Maarit Karonen, Juha-Pekka Salminen   +2 more
doaj   +1 more source

Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS. [PDF]

PLoS ONE, 2015
Hydrophilic interaction-ultra high performance liquid chromatography (HILIC-UHPLC) allows the analysis of highly polar metabolites, providing complementary information to reversed-phase (RP) chromatography.
Longshan Zhao, Zhili Xiong, Xiumei Lu, Shuning Zheng, Fang Wang, Lin Ge, Guangyue Su, Jingyu Yang, Chunfu Wu   +8 more
doaj   +1 more source