Results 51 to 60 of about 2,976,642 (307)
Exploring jujube wine flavor and fermentation mechanisms by HS-SPME-GC–MS and UHPLC-MS metabolomics
Food Chemistry: XHighlights • GC–MS and LC-MS revealed the quality changes of jujube wine during fermentation.• A total of 107 volatile substances and 1758 non-volatile substances were identified.• The type of jujube wine aroma changes from grassy and mushroomy to floral
Xin-Xin Zhao +5 more
semanticscholar +1 more source
, 2023 This manuscript describes a novel and simple strategy for optimizing the determination of contaminants in groundwater using online solid-phase extraction (SPE) coupled with ultrahigh-performance liquid chromatography (UHPLC) and tandem mass spectrometry (
Cyntia Cabral Ribeiro (17333074) +17 more
core +1 more source
Journal of Extracellular Vesicles, 2019 Liver constitutes the major metabolic factory in the organism and is involved in the synthesis, secretion and clearance of many blood-circulating molecules.
Felix Royo +8 more
doaj +1 more source
Journal of Antimicrobial Chemotherapy, 2020 Background Remdesivir has received significant attention for its potential application in the treatment of COVID-19, caused by SARS-CoV-2. Remdesivir has already been tested for Ebola virus disease treatment and found to have activity against SARS and ...
V. Avataneo +10 more
semanticscholar +1 more source
Characterization of multiple chemical components of GuiLingJi by UHPLC-MS and 1H NMR analysis
Journal of Pharmaceutical Analysis, 2021 GuiLingJi (GLJ), a classic traditional Chinese medicine (TCM) formula, is composed of over 20 herbs, according to the Pharmacopeia of the People's Republic of China.
Jing-Chao Shi +4 more
semanticscholar +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Applied SciencesA rapid ultra-high-performance liquid chromatography method with diode-array (DAD) and tandem mass spectrometric (MS/MS) detection was developed and, for the first time, applied for the determination of potassium iodide in ophthalmic formulations.
Jordan Sycz +2 more
doaj +1 more source
Journal of the American Society for Mass SpectrometryExtracts prepared from the seeds of the medicinal plant milk thistle [Silybum marianum (L.) Gaertn. (Asteraceae)] are widely used as dietary supplements due to anti-inflammatory, antitumor, and hepatoprotective effects.
R. Muchiri, R. V. van Breemen
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Advanced Science, EarlyView.This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan +17 more
wiley +1 more source