Results 211 to 220 of about 12,472,827 (321)

Scoping review of public attitudes to government active travel interventions in the UK. [PDF]

BMJ Open
Morris N, Jago R, Russell HP, Salway R, Morgan K, Kipping R.   +5 more
europepmc   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Group Poetry and Quilt-Making -Creative Public Involvement Approaches to Contentious Concepts in Frailty Research. [PDF]

Health Expect
Lammons W, Arnold L, Mcmullen S, Aspinal F, Begum S, Barrett K, Walters K, Clegg A, Mackay-Thomas S, Humphrey S, Nimmons D.   +10 more
europepmc   +1 more source

Assessing uncertainty in housing stock infiltration rates and associated heat loss: English and UK case studies

, 2015
B. Jones, P. Das, Z. Chalabi, M. Davies, I. Hamilton, R. Lowe, A. Mavrogianni, D. Robinson, Jonathon Taylor   +8 more
semanticscholar   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Translation and interpreting services must be considered across the lifecycle of clinical trials. [PDF]

Trials
Roberts K, Lewis R, Iqbal G, Rick C, Shepherd V.   +4 more
europepmc   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

A full review of online OPAT educational resources for patients and healthcare professionals in the grey literature revealing resource gaps. [PDF]

JAC Antimicrob Resist
Watson C, Spencer-Jones J, Heard K, Jenkins A, Gauthier TP, Rogers BA, Nor ANM, Sime FB, Gilchrist M.   +8 more
europepmc   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot, Désanka M. Stoppels, Arno R. Bourgonje, Willemien F. J. Hof, Martin C. J. Kneyber, Daan J. Touw, Henkjan J. Verkade, Paola Mian   +7 more
wiley   +1 more source

Jurisdiction in Employment Matters Post-Brexit. [PDF]

Oxf J Leg Stud
Grušić U.
europepmc   +1 more source