Results 21 to 30 of about 20,711,708 (259)

Outcomes in Paediatric Intensive Care Units for Children with Life-Limiting Conditions: A national data linkage study

International Journal of Population Data Science, 2017
Objective To identify children with a Life-Limiting Condition (LLC) who have had an admission to a Paediatric Intensive Care Unit (PICU) in England and their outcomes.
Lorna Fraser, Sarah Fleming, Roger Parslow   +2 more
doaj   +1 more source

Generation of evidence supporting the content validity of SF-36, FACIT-F, and LupusQoL, and novel patient-reported symptom items for use in patients with systemic lupus erythematosus (SLE) and SLE with lupus nephritis (LN)

Lupus Science and Medicine, 2022
Objective SLE and lupus nephritis (LN) have significant impacts on the health-related quality of life of patients living with the condition, which are important to capture from the patient’s perspective using patient-reported outcomes (PROs).
Vibeke Strand, Anna Roberts, Zahi Touma, Amy Ward, Pamela Berry, Rebecca Williams-Hall, Nicola Williamson, Melissa Barclay, Adam Gater, Chloe Tolley, Helena Bradley, Elizabeth Hsia, Qing Zuraw, Patricia DeLong   +13 more
doaj   +1 more source

Cancer Research UK Cancer Awareness Measures, 2019

, 2021
copyright UK Data Service and data collection copyright owner.The Cancer Awareness Measure (CAM) was developed in 2007-8 to address the absence of a validated measure of general public awareness of cancer (Stubbings, S., Robb, K., Waller, J., Ramirez, A.,
Cancer Research UK
core   +2 more sources

A novel protocol for a "Citizen Panel" for diverse Public and Participant Involvement in the review and development of the process to access data in the UK Longitudinal Linkage Collaboration Trusted Research Environment

International Journal of Population Data Science
Background Researchers can apply to UK Longitudinal Linkage Collaboration (UK LLC) to access Longitudinal Population Study (LPS) data linked to health, non-health administrative and geo-environmental data.
Lidis Garbovan, Betty O. Idemudia, Robin Flaig, Kirsteen Campbell, Katharine Evans, Andy Boyd, Sarah Cunningham-Burley, Emma L. Turner   +7 more
doaj   +1 more source

Atrial Fibrillation in Patients With Cardiomyopathy: Prevalence and Clinical Outcomes From Real‐World Data

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Cardiomyopathy is a common cause of atrial fibrillation (AF) and may also present as a complication of AF. However, there is a scarcity of evidence of clinical outcomes for people with cardiomyopathy and concomittant AF. The aim of the present
Benjamin J. R. Buckley, Stephanie L. Harrison, Dhiraj Gupta, Elnara Fazio‐Eynullayeva, Paula Underhill, Gregory Y. H. Lip   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Using digital information to enrich longitudinal population study data at the UK Longitudinal Linkage Collaboration

International Journal of Population Data Science
Introduction & Background UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment (TRE) for the longitudinal research community.
Abigail Hill, Andy Boyd, Richard Thomas, Katherine Evans, Rachel Calkin   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Analysis of the Bankruptcy Procedures of Legal Entities in Russia in the Years 2010-2016

Учёт. Анализ. Аудит, 2019
The article discusses the dynamics of the enterprises that are being opened or liquidated due to bankruptcy in Russia in 2010-2016. A detailed analysis of the changes and observed trends throughout the study period is conducted in the article ...
Ekaterina Adreevna Karzaeva
doaj   +1 more source