Results 41 to 50 of about 20,711,708 (259)

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

A Novel Drug‐Loaded Porous Parylene Electrode for Targeted Anti‐Inflammatory Therapy and Hearing Preservation in Cochlear Implantation

Advanced Healthcare Materials, EarlyView.
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang, Ying‐Chang Lu, Yu‐Ming Chang, Yen‐Hui Chan, Hong‐Yu Yan, Yi‐Shan Lee, Pei‐Hsuan Lin, Cheng‐Yu Hsieh, Chuan‐Jen Hsu, Tien‐Chen Liu, Hsien‐Yeh Chen, Chen‐Chi Wu   +11 more
wiley   +1 more source

Understanding Longitudinal Population Study Data and the Law

International Journal of Population Data Science
Background UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment for the UK's longitudinal studies. The need for a clear way to communicate Longitudinal Population Study (LPS) participants’ rights was identified ...
Kirsteen Campbell, Rebecca Whitehorn, Sarah Chave, Michael Gregg, Mhairi Docherty, Rosie Hill, Emma Turner, Katharine Evans, Jacqui Oakley, Robin Flaig, Andy Boyd   +10 more
doaj   +1 more source

Evolution of OLED Lamination Technology With Development of Display Form Factors

Advanced Materials Technologies, EarlyView.
This review evaluates the evolution of organic light‐emitting diode (OLED) lamination technologies alongside advancing display form factors. It contrasts optically clear adhesives and resins, highlighting uniformity control for rigid screens, bubble‐free optimization for bended architectures, and visible‐light curing for foldable layers.
Kwan‐Young Han, Ji‐Hoon Park
wiley   +1 more source

Modern instrumentation and practical application of flame atomic emission spectrometry

Chimica Techno Acta
The modern instrumentation for flame atomic emission spectrometry (FAES) is overviewed: the main technical (composition of the fuel gas used, dispersing element, number of analytical channels, reference channel, detecting element, sampling method) and ...
E. A. Zauer
doaj   +1 more source

Seven‐Fold Compression of Mid‐Infrared Pulses Using a Series of Titanium Dioxide Plates

Advanced Optical Materials, EarlyView.
Here, a sequence of three titanium dioxide plates is used to compress a mid‐infrared pulse from 103.9 femtoseconds to 14.1 femtoseconds (about two optical cycles) without the use of external dispersion compensation. The approach maintains high efficiency and produces pulses with a stable carrier‐envelope phase, providing a compact platform for ...
André M. Côté, Dillon Lim, Nicholas Karpowicz, Gary W. Leach, Shawn Sederberg   +4 more
wiley   +1 more source

ADRUK Ingest Improvement Task and Finish Group: Smoothing the ingest of data

International Journal of Population Data Science
Objectives Analysts ingest data to TREs for research; extract, process and curate public sector data then made accessible to researchers in safe environments. Although differences surround each dataset, the processes can be made broadly replicable.
Jen Bishop, Linus Chirchir, Rachel Coey, Amy Dunlop, Hywel Evans, David Grzybowski, Alan Harbinson, Cristina Magder, Nichola McCullough, Richard McFerran, Jen Muir, Alex Ramage, Stella Telford, Richard Thomas, Tudor Vilcan   +14 more
doaj   +1 more source

Development of the drilling mud composition for directional wellbore drilling considering rheological parameters of the fluid

Записки Горного института, 2020
Article presents investigations on the development of a drilling mud composition for directional wells in an oil field located in the Republic of Tatarstan (Russia).
Nadezhda M. Ulyasheva, Ekaterina L. Leusheva, Ramil N. Galishin   +2 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source