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UK Longitudinal Linkage Collaboration (UK LLC): The National Trusted Research Environment for Longitudinal Research [PDF]

International Journal of Population Data Science
IntroductionThe UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment (TRE) for the UK's longitudinal research community, supporting the UK's unparalleled collection of Longitudinal Population Studies (LPS). Initially set up as a COVID-19 research resource, UK LLC is now a generic database for any research for the ...
Andy Boyd, Katharine Evans, Emma L. Turner, Robin Flaig, Jacqui Oakley, Kirsteen C. Campbell, Richard Thomas, Stela McLachlan, Matthew Crane, Rebecca Whitehorn, Rachel Calkin, Abigail Hill, Samantha Berman, David Ford, Martin Tobin, David Porteous, Danielle F. Gomes, Maria-Paz Garcia, Andrew Wong, Aida Sanchez, Chris Orton, Simon Thompson, John Gulliver, Kathryn Adams, Ellena Badrick, Chiara Batini, Michaela Benzeval, Susie Boatman, Gerome Breen, Shannon Bristow, Abigail Britten, Luke Bryant, Adam Butterworth, Archie Campbell, Sarah Chave, John Danesh, Jayati Das-Munshi, Karen Dennison, Emanuele Di Angelantonio, Thalia C. Eley, Helen Fisher, Emla Fitzsimons, Alissa Goodman, Michael Gregg, Anna L Guyatt, Anna Hansell, Rebecca Harmston, Andy Heard, Morag Henderson, Rosie Hill, Szu-Chia Huang, Catherine John, Frank Kee, Nathalie Kingston, Jack Kneeshaw, Rashmi Kumar, Genevieve Lachance, Celestine Lockhart, Hazel Lockhart-Jones, Sarah Markham, Dan Mason, Bernadette McGuinness, Maisie McKenzie, Amy McMahon, Chelsea Mika Malouf, Mark Mumme, Charlotte Neville, Kate Northstone, Zoe Oldfield, Dara O’Neill, Manish Pareek, John Pickavance, Yasmin Rahman, Holly Reilly, Angela Scott, Deb Smith, Andrew Steptoe, Claire Steves, Cathie Sudlow, Gerald Sze, Nicholas L. Timpson, Tapiwa Tungamirai, Laura Venn, Matthew Walker, Neil Walker, Nicolas Wareham, Aidan Watmuff, Tony Webb, Karen Williams, John Wright, Darioush Yarand, George B Ploubidis, John Macleod, Jonathan AC. Sterne, Nishi Chaturvedi   +94 more
openaire   +6 more sources

A novel protocol for a "Citizen Panel" for diverse Public and Participant Involvement in the review and development of the process to access data in the UK Longitudinal Linkage Collaboration Trusted Research Environment [PDF]

International Journal of Population Data Science
Background Researchers can apply to UK Longitudinal Linkage Collaboration (UK LLC) to access Longitudinal Population Study (LPS) data linked to health, non-health administrative and geo-environmental data. This paper describes the protocol for the "UK LLC Citizen Panel": a new method of incorporating a diverse public in decisions about the ...
Lidis Garbovan, Betty O. Idemudia, Robin Flaig, Kirsteen Campbell, Katharine Evans, Andy Boyd, Sarah Cunningham-Burley, Emma L. Turner   +7 more
openaire   +3 more sources

The UK Longitudinal Linkage Collaboration: A trusted research environment for the longitudinal research community

International Journal of Population Data Science, 2022
ObjectivesOur Trusted Research Environment (TRE) provides a centralised infrastructure to pool Longitudinal Population Studies’ (LPS) data and systematically link participants’ routine health, administrative and environmental records. All data are held in a centralised research resource which is now certified by UK Statistics Authority as meeting the ...
Andy Boyd, Robin Flaig, Jacqui Oakley, Kirsteen Campbell, Katharine Evans, Stella McLachlan, Richard Thomas, Emma Turner   +7 more
openaire   +3 more sources

UK Longitudinal Linkage Collaboration – and the challenges in creating a new Longitudinal Populations Studies linked data resource.

International Journal of Population Data Science, 2022
ObjectivesThe UK Longitudinal Linkage Collaboration (UK LLC) is a new, unprecedented infrastructure enabling research into the COVID-19 pandemic. The UK LLC integrates data from >20 UK longitudinal studies with systematically linked health, administrative and environmental records to facilitate cross-disciplinary COVID-19 research for accredited UK ...
Robin Flaig, Jacqui Oakley, Kirsteen Campbell, Katharine Evans, Stela McLachlan, Richard Thomas, Emma Turner, Andy Boyd   +7 more
openaire   +2 more sources

How public and participant voices have influenced the UK Longitudinal Linkage Collaboration and its Trusted Research Environment.

International Journal of Population Data Science, 2022
ObjectivesUK longitudinal population studies have complex governance structures and participant safeguards. As a new Trusted Research Environment (TRE) for >20 longitudinal studies, the UK Longitudinal Linkage Collaboration (UK LLC) must ensure effective public/participant input to make central design and operational decisions whilst retaining ...
Kirsteen Campbell, Rebecca Whitehorn, Andy Boyd, Robin Flaig, Stela McLachlan, Christie Levein, Jacqueline Oakley, Sarah Chave, Michael Gregg, Della Ogunleye   +9 more
openaire   +2 more sources

The UK Longitudinal Linkage Collaboration legal & governance framework: managing ‘delegated and distributed’ data processing working with cross-sectorial data owners.

International Journal of Population Data Science, 2022
ObjectivesThe UK Longitudinal Linkage Collaboration (UKLLC) was established to link and integrate data from many longitudinal population studies (LPS) with participants’ records from diverse governmental data owners across the UK. The UKLLC aims to unify disparate requirements from many data owners in different legal jurisdictions into one, predictable,
Jacqui Oakley, Robin Flaig, Emma Turner, Kirsteen Campbell, Katharine Evans, Stela McLachlan, Richard Thomas, Andrew Boyd   +7 more
openaire   +2 more sources

Informing the ‘early years’ agenda in Scotland: understanding infant feeding patterns using linked datasets [PDF]

, 2013
Background: Providing infants with the ‘best possible start in life’ is a priority for the Scottish Government. This is reflected in policy and health promotion strategies to increase breast feeding, which gives the best source of nutrients for healthy ...
Ajetunmobi, Omotomilola, Chalmers, James, Fleming, Michael, Stockton, Diane, Whyte, Bruce, Wood, Rachel   +5 more
core   +1 more source

Common variation near ROBO2 is associated with expressive vocabulary in infancy [PDF]

, 2014
Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are unknown. Here we conduct a genome-wide screen and follow-up study of expressive vocabulary in toddlers
Ang, Qi W., Cents, Rolieke A. M., Dale, Philip S., Davis, Oliver S. P., Evans, David M., Golding, Jean, Haworth, Claire M. A., Hofman, A., Jaddoe, Vincent Wilfred Vishal-Kapoor, Jarvelin, Marjo-Riitta, Kemp, John P., Meaburn, Emma L., Miller, Laura, O’Reilly, Paul F., Pennell, Craig E., Pillas, Demetris, Plomin, Robert, Price, Tom S., Ring, Susan M., Rivadeneira, Fernando, Rodriguez, Alina, Roulstone, Susan, Smith, George Davey, St Pourcain, Beate, Tiemeier, Henning, Timpson, Nicholas J., Velders, F. P., Verhulst, F. C., Warrington, Nicole M., Whitehouse, Andrew J. O., Wren, Yvonne, Yliherva, Anneli   +31 more
core   +10 more sources

Learning from openness : the dynamics of breadth in external innovation linkages [PDF]

, 2014
We explore how openness in terms of external linkages generates learning effects, which enable firms to generate more innovation outputs from any given breadth of external linkages.
Chesbrough H, Griliches Z, Hippel E, Nelson RR, Simon HA   +4 more
core   +2 more sources

Common Genetic Variants Explain the Majority of the Correlation Between Height and Intelligence : The Generation Scotland Study [PDF]

, 2014
Creative Commons Attribution LicensePeer reviewedPublisher ...
Archie Campbell, B Benyamin, BH Smith, BH Smith, C Gale, Caroline Hayward, CM Calvin, CM Calvin, CM Haworth, CM Lee, D Wechsler, D Wechsler, David J. Porteous, E Whitley, G Davies, G. David Batty, GD Batty, Ian J. Deary, IJ Deary, IJ Deary, J Yang, J Yang, JC Raven, JM Starr, JM Sundet, JP Beauchamp, K Silventoinen, K Silventoinen, KL Gunderson, LJ Whalley, Lynne J. Hocking, M Trzaskowski, MC Keller, MD Lezak, Peter M. Visscher, Riccardo E. Marioni, S Macgregor, SH Lee, Shona M. Kerr, SM Kerr, TA Paajanen   +40 more
core   +3 more sources