Results 11 to 20 of about 55,804 (221)

Electronic health records to facilitate clinical research [PDF]

, 2016
Electronic health records (EHRs) provide opportunities to enhance patient care, embed performance measures in clinical practice, and facilitate clinical research. Concerns have been raised about the increasing recruitment challenges in trials, burdensome
Blomster, Juuso I., Cowie, Martin R., Curtis, Lesley H., Duclaux, Sylvie, Ford, Ian, Fritz, Fleur, Goldman, Samantha, Janmohamed, Salim, Kreuzer, Jörg, Leenay, Mark, Michel, Alexander, Ong, Seleen, Pell, Jill P., Southworth, Mary Ross, Stough, Wendy Gattis, Thoenes, Martin, Zalewski, Andrew, Zannad, Faiez   +17 more
core   +2 more sources

Optimizing patient risk stratification for colonoscopy screening and surveillance of colorectal cancer: The role for linked data [PDF]

, 2017
No abstract available for this ...
Cameron Platell, David B. Preen, Dayna R. Cenin, Dayna R. Cenin, Hooi C. Ee, Iris Lansdorp-Vogelaar, Lakkhina Troeung, Max Bulsara, Max Bulsara, Peter O’Leary   +9 more
core   +3 more sources

Variation in compulsory psychiatric inpatient admission in England:a cross-sectional, multilevel analysis [PDF]

, 2014
Background: Rates of compulsory admission have increased in England in recent decades, and this trend is accelerating. Studying variation in rates between people and places can help identify modifiable causes.
Bhui, K., Crepaz-keay, D., Cyhlarova, E., Keown, P., Mcbride, O., Parsons, H., Scott, J., Twigg, Liz, Weich, S.   +8 more
core   +2 more sources

The Belfast Youth Development Study (BYDS): A prospective cohort study of the initiation, persistence and desistance of substance use from adolescence to adulthood in Northern Ireland [PDF]

, 2018
Background: Substance misuse persists as a major public health issue worldwide with significant costs for society. The development of interventions requires methodologically sound studies to explore substance misuse causes and consequences. This Cohort
Higgins, Kathryn, Jordan, Julie Anne, McCann, Mark, McCartan, Claire, McLaughlin, Aisling, Percy, Andrew, Perra, Oliver   +6 more
core   +4 more sources

Community environment, cognitive impairment and dementia in later life: results from the Cognitive Function and Ageing Study [PDF]

, 2015
Background: Few studies have investigated the impact of the community environment, as distinct from area deprivation, on cognition in later life. This study explores cross-sectional associations between cognitive impairment and dementia and environmental
,, Barnes, Linda E., Brayne, Carol, Jones, Andrew P., Matthews, Fiona E., Prina, A. Matthew, Wu, Yu-Tzu   +6 more
core   +1 more source

The Scottish school leavers cohort: linkage of education data to routinely collected records for mortality, hospital discharge and offspring birth characteristics [PDF]

, 2017
Purpose: The Scottish school leavers cohort provides population-wide prospective follow-up of local authority secondary school leavers in Scotland through linkage of comprehensive education data with hospital and mortality records.
Dundas, Ruth, Leyland, Alastair H., Stewart, Catherine H.   +2 more
core   +1 more source

“It is better to die”: experiences of traditional health practitioners within the HIV treatment as prevention trial communities in rural South Africa (ANRS 12249 TasP trial) [PDF]

, 2016
The ANRS 12249 Treatment-as-Prevention (TasP) cluster-randomized trial in rural South Africa uses a “test and treat” approach. Home-based testing services and antiretroviral treatment initiation satellite clinics were implemented in every cluster as part
Collins Iwuji, Joanna Orne-Gliemann, Joseph Larmarange, Mosa Moshabela, Nuala McGrath, null null, Thembelihle Zuma   +6 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Palliative care needs in patients hospitalized with heart failure (PCHF) study: rationale and design [PDF]

, 2015
Aims The primary aim of this study is to provide data to inform the design of a randomized controlled clinical trial (RCT) of a palliative care (PC) intervention in heart failure (HF).
Campbell, Ross T., Davidson, Patricia M., Denvir, Martin A., Ford, Ian, Gardner, Roy S., Hogg, Karen J., Jackson, Colette E., Johnson, Miriam J., McMurray, John J.V., Petrie, Mark C., Wright, Ann   +10 more
core   +3 more sources