Results 111 to 120 of about 558,447 (316)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Media and information literacy policies in the UK
, 2014 This is a position paper on the capacity for media and information education in the UK in 2014 to facilitate media, digital and information literacy as defined by the European Commission (EC) and on the relationship between UK media/information education,
McDougall, Julian, Livingstone, Sonia
core
Health Literacy and Communication OpenBackground Health literacy is widely recognised as a social determinant of health and a key factor in health communication and education, with low health literacy correlated with poor health outcomes and socioeconomic inequalities.
Onyinye Chiweta-Oduah, Steven Buchanan
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Dynamic Capabilities; exploring media industry level capabilities
, 2014 The competitive dynamics of many industries have changed considerably over the past decade, and perhaps, none more so than in the Media Industry. Industries have long been examined by researchers from a strategic perspective with various themes of ...
Oliver, John James
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Towards a Psychoanalytic Concept of Affective-Digital Labour
Media and Communication, 2018 This article draws on the argument that users on corporate social media conduct labour through the sharing of user-generated content. Critical political economists argue that such acts contribute to value creation on social media and are therefore to be ...
Jacob Johanssen
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
, 2011 A new CMCS study led by researcher Amy Brouillette analyses the consistency of the Hungarian media regulations with European practices and norms. It addresses a key international policy debate regarding the conformity of Hungary’s new media legislation ...
Center for Media and Communication Studies
core
The economics and regulations of concentrations of media ownership in the UK [PDF]
, 1997 Since the early 1990s, regulators in the UK and in many other countries have faced increasing pressure from media industry participants to liberalise media and cross-media ownership restrictions.
Doyle, Gillian
core
Regulating Against Offence: lessons from the field of UK advertising
, 2007 This article looks at the question of offence in UK advertising. It examines what constitutes offence, who claims to be offended, and on whose behalf.
Amy-Chinn, Dee
core +1 more source