Results 51 to 60 of about 26,714,216 (288)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Collaborative Design in Kinetic Performance: Safeguarding the Uilleann Pipes through Inertial Motion Capture

open access: yesMultimodal Technologies and Interaction, 2022
This paper explores the possibilities of motion capture as a tool to preserve and study Intangible Cultural Heritage (ICH) practices such as playing instruments.
Philip I. Morris   +1 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

BBC charter review: public consultation [PDF]

open access: yes, 2015
The constitutional basis of the BBC is the Royal Charter, which is due to expire at the end of 2016. This consultation paper therefore seeks to engage the UK in a dialogue about the future of the BBC. The BBC is one of the great institutions of Britain,
Department for Culture Media and Sport (UK)
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A Deep Learning Approach for Network Intrusion Detection Using a Small Features Vector

open access: yesJournal of Cybersecurity and Privacy, 2023
With the growth in network usage, there has been a corresponding growth in the nefarious exploitation of this technology. A wide array of techniques is now available that can be used to deal with cyberattacks, and one of them is network intrusion ...
Humera Ghani   +2 more
doaj   +1 more source

An Analysis of UK Policing Engagement via Social Media [PDF]

open access: yes, 2017
Police forces in the UK make use of social media to communicate and engage with the public. However, while guidance reports claim that social media can enhance the accessibility of policing organisations, research studies have shown that exchanges between the citizens and the police tend to be infrequent.
Miriam Fernández   +2 more
openaire   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Evaluating Awareness and Perception of Botnet Activity within Consumer Internet-of-Things (IoT) Networks

open access: yesInformatics, 2019
The growth of the Internet of Things (IoT), and demand for low-cost, easy-to-deploy devices, has led to the production of swathes of insecure Internet-connected devices.
Christopher D. McDermott   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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