Results 51 to 60 of about 558,447 (316)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
A Deep Learning Approach for Network Intrusion Detection Using a Small Features Vector
With the growth in network usage, there has been a corresponding growth in the nefarious exploitation of this technology. A wide array of techniques is now available that can be used to deal with cyberattacks, and one of them is network intrusion ...
Humera Ghani +2 more
doaj +1 more source
An Analysis of UK Policing Engagement via Social Media [PDF]
Police forces in the UK make use of social media to communicate and engage with the public. However, while guidance reports claim that social media can enhance the accessibility of policing organisations, research studies have shown that exchanges between the citizens and the police tend to be infrequent.
Miriam Fernández +2 more
openaire +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
How the mass media report social statistics: A case study concerning research on end-of-life decisions [PDF]
This is the post-print version of the final paper published in Social Science & Medicine. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Clive Seale, Seale, C, Seale, Clive
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
CONCEPTUAL METAPHOR IN THE UK MEDIA TEXTS.
This article explores the pervasive influence of conceptual metaphors within the realm of UK media texts. Drawing on cognitive linguistics and media studies, we delve into how metaphorical expressions shape the narrative structure and communication strategies employed by various media outlets.
To`rayeva, Maftuna, Yugay, Yevgeniya
openaire +2 more sources
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The rapid expansion of Internet of Things (IoT) technologies has introduced significant challenges in understanding the complexity and structure of network traffic data, which is essential for developing effective cybersecurity solutions.
Humera Ghani +2 more
doaj +1 more source

