Results 51 to 60 of about 26,714,216 (288)
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
This paper explores the possibilities of motion capture as a tool to preserve and study Intangible Cultural Heritage (ICH) practices such as playing instruments.
Philip I. Morris +1 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
BBC charter review: public consultation [PDF]
The constitutional basis of the BBC is the Royal Charter, which is due to expire at the end of 2016. This consultation paper therefore seeks to engage the UK in a dialogue about the future of the BBC. The BBC is one of the great institutions of Britain,
Department for Culture Media and Sport (UK)
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A Deep Learning Approach for Network Intrusion Detection Using a Small Features Vector
With the growth in network usage, there has been a corresponding growth in the nefarious exploitation of this technology. A wide array of techniques is now available that can be used to deal with cyberattacks, and one of them is network intrusion ...
Humera Ghani +2 more
doaj +1 more source
An Analysis of UK Policing Engagement via Social Media [PDF]
Police forces in the UK make use of social media to communicate and engage with the public. However, while guidance reports claim that social media can enhance the accessibility of policing organisations, research studies have shown that exchanges between the citizens and the police tend to be infrequent.
Miriam Fernández +2 more
openaire +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
The growth of the Internet of Things (IoT), and demand for low-cost, easy-to-deploy devices, has led to the production of swathes of insecure Internet-connected devices.
Christopher D. McDermott +2 more
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

