Results 51 to 60 of about 359,193 (314)

Has there been an economic dividend from devolution? [PDF]

open access: yes, 2012
It is now over twelve years since the restoration of Scotland's parliament, after a hiatus of almost three centuries. Sufficient time has therefore elapsed that it is possible to provide some evidence on whether Scotland's economy has indeed performed ...
Armstrong, Jo   +3 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The fixed term Parliaments Act and votes of confidence [PDF]

open access: yes, 2015
The Government in the UK rests for its continuation in office on the confidence of the House of Commons. Until 2011, it was a convention of the constitution that a Government defeated on a motion of confidence resigned or requested the dissolution of ...
Norton, Philip
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Managing Disintegration: How the European Parliament Responded and Adapted to Brexit

open access: yesPolitics and Governance, 2021
Brexit makes both a direct and an indirect impact on the European Parliament (EP). The most direct consequence is the withdrawal of the 73-member strong UK contingent and the changing size of the political groups.
Edoardo Bressanelli   +2 more
doaj   +1 more source

There is no such thing as the ‘will of the people’ – Brexit needs the involvement of parliament [PDF]

open access: yes, 2016
Theresa May has rejected calls for the UK parliament to have a vote on the terms of Brexit, however on 12 October she accepted that there will be an opportunity for parliament to debate the country’s strategy before Article 50 is triggered.
Larcinese, Valentino
core  

A crisis of parliament [PDF]

open access: yes, 2014
In this chapter the institution of Parliament is located within the broader ideational frames of parliamentarism and parliamentary democracy in order to examine the contestability of the notion of parliamentary crisis in the UK.
Judge, David
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

MPs pay has risen sharply since the 1970s – but it is outside earnings that should really concern [PDF]

open access: yes, 2013
There is a long tradition of elected representatives in the UK drawing income from activities ‘external’ to their work in parliament. In part, this tradition reflects the belated acceptance of a need to pay MPs a full salary.
Blick, Andrew   +2 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

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