Results 51 to 60 of about 516,753 (367)

Oropharynx Ulceration [PDF]

Journal of Education and Teaching in Emergency Medicine, 2017
History of present illness: A 31-year-old male presented to the emergency department (ED) with worsening constant left sided throat pain over the past four months. The patient reports that he was brushing his teeth when his dog jumped onto his back causing his toothbrush to puncture the back of his throat, resulting in immediate bleeding and discomfort.
Sylwanowicz, Lauren, Wong, Andrew
openaire   +4 more sources

Modern management of diabetic foot complications [PDF]

Journal of Clinical and Investigative Surgery, 2019
Diabetes mellitus comprises a heterogeneous group of metabolic abnormalities, characterized by chronic hyperglycemia, resulting from a deficiency in insulin secretion, a deficiency in action, or from both situations.
Cristian Bălălău, Nicolae Bacalbașa, Carolina Negrei, Bianca Gălățeanu, Octav Ghinghină, Oana-Denisa Bălălău, Ioana Păunică, Marinela Chioveanu   +7 more
doaj   +1 more source

Hybrid Classical-Quantum method for Diabetic Foot Ulcer Classification [PDF]

arXiv, 2021
Diabetes is a raising problem that affects many people globally. Diabetic patients are at risk of developing foot ulcer that usually leads to limb amputation, causing significant morbidity, and psychological distress. In order to develop a self monitoring mobile application, it is necessary to be able to classify such ulcers into either of the ...
arxiv  

Mathematical Modelling of Different Types of Body Support Surface for Pressure Ulcer Prevention [PDF]

, 2014
Pressure ulcer is a common problem for today’s healthcare industry. It occurs due to external load applied to the skin. Also when the subject is immobile for a longer period of time and there is continuous load applied to a particular area of human body,
Cole, Jonathan, Dubey, Venketesh N., Hickish, Tamas F., Mishu, Mahbub C.   +3 more
core   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

The Effect of Tramadol and Indomethacin Coadministration on Gastric Barrier Function in Dogs

Journal of Veterinary Internal Medicine, 2014
Background Tramadol is a centrally acting analgesic that is often used in conjunction with nonsteroidal anti‐inflammatory drugs (NSAIDs). The effect of coadministration of tramadol and indomethacin on gastric barrier function in dogs is unknown ...
T.L. Hill, B.D.X. Lascelles, J. M. Law, A.T. Blikslager   +3 more
doaj   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

EPUAP classification system for pressure ulcers: European reliability study [PDF]

, 2007
‘The definitive version is available at www3.interscience.wiley.com .' Copyright Blackwell PublishingPeer ...
Bates-Jensen B.M, Bennett R.G., Black J., Bours G.J., Collier M., Dealey C., Derre B., Donnelly J., European Pressure Ulcer Advisory Panel (EPUAP), Fletcher J., Guggenmoos-Holzmann I., Maklebust J., National Pressure Ulcer Advisory Panel., Polit D.F., Russell L., Sharp A., Witkowski J.A., Wound, Ostomy, and Continence Nurses Society (WOCN)   +17 more
core   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source