In Search of Newer Targets for IBD: A Systems and a Network Medicine Approach [PDF]
Introduction: Crohn's disease and ulcerative colitis, both under the umbrella of inflammatory bowel diseases (IBD), involve many distinct molecular processes. The difference in their molecular processes is studied by using the different genes involved in each disease, and it is explored further for drug targeting and drug repurposing.
arxiv
Differential expression of prolyl hydroxylase 1 in patients with ulcerative colitis versus patients with Crohn's disease/infectious colitis and healthy controls [PDF]
Background: Inhibition of prolyl hydroxylases (PHDs) leads to the induction of a transcriptional program that, in the gut, promotes intestinal epithelial cell survival.
De Vos, Martine+4 more
core +2 more sources
Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview [PDF]
C.R.C. was funded by the Derek Willoughby Fund for Inflammatory Research. A.L.H. and T.A.G.
Ailsa L Hart+31 more
core +1 more source
Statistics of Ulcerative Colitis from the London Hospitals, Provided to Form a Basis for the above Discussion: Guy's Hospital [PDF]
Hilary Cameron, C. H. Rippmann
openalex +1 more source
Ordinal Multiple-instance Learning for Ulcerative Colitis Severity Estimation with Selective Aggregated Transformer [PDF]
Patient-level diagnosis of severity in ulcerative colitis (UC) is common in real clinical settings, where the most severe score in a patient is recorded. However, previous UC classification methods (i.e., image-level estimation) mainly assumed the input was a single image.
arxiv
Treatment of Ulcerative Colitis with Local Hydrocortisone [PDF]
S. C. Truelove
openalex +1 more source
Non-Invasive monitoring of Inflammatory Bowel Disease : time to use newer tools? [PDF]
Introduction: In inflammatory bowel disease (IBD), commonly used biomarkers employed for non-invasive monitoring of disease activity are the C-reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR). Ulcerative colitis (UC) has a modest to absent
Azzopardi, Neville
core
Mucosal adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG in the human colonic mucosa. A proof-of-concept study [PDF]
AIM To investigate the adhesion and anti-inflammatory effects of Lactobacillus rhamnosus GG (LGG) in the colonic mucosa of healthy and ulcerative colitis (UC) patients, both in vivo and ex vivo in an organ culture model.
Corleto, Vito Domenico+6 more
core +1 more source
HLA TYPING OF ULCERATIVE COLITIS IN IRAN
Ulcerative colitis is an acute or chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of ulcerative colitis is unknown.
Froutan+4 more
doaj