Results 101 to 110 of about 219,955 (289)

ULCERATIVE COLITIS IN CHILDREN [PDF]

, 2009
Chronic nonspecific ulcerative colitis remaine a disease of unkown etiology, although much new information continues to be gleaned from basic research and clinical trials. In most instances, ulcerative colitis respond to medical therapy.
Florea Iordăchescu
core   +2 more sources

Oral Astilbin Nanogels Modulate Senescence‐Associated CD4+ T Cells and Promote Treg Induction in Aged Mice with Colitis

Advanced Science, EarlyView.
Fluorinated β‐glucan/pectin nanogels enable colon‐targeted oral delivery of astilbin through gastrointestinal protection, β‐glucanase‐responsive release, mucus penetration, and prolonged retention. The released astilbin attenuates senescence‐associated features of CD4+ T cells and promotes Treg responses, while the nanogel matrix modulates the gut ...
Lei Zhao, Xinyun Zhang, Qian Ren, Xue Song, Meifang Zhao, Rongshen Wang, Haocheng Du, Yan Chen, Peigen Xu, Jiangyun Liu, Jian Zhang, Jingjing Ma   +11 more
wiley   +1 more source

Identification of symptom domains in ulcerative colitis that occur frequently during flares and are responsive to changes in disease activity

Health and Quality of Life Outcomes, 2008
Background Ulcerative colitis disease activity is determined by measuring symptoms and signs. Our aim was to determine which symptom domains are frequent and responsive to change in the evaluation of disease activity, which are those defined by three ...
Wang Sijian, Zimmermann Ellen M, Dave Maneesh, Wren Patricia A, Khan Tahira, Waljee Akbar K, Joyce Joel C, Zhu Ji, Higgins Peter DR   +8 more
doaj   +1 more source

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

The Compartive Study of Prevalence of Ulcerative Colitis in General Population with MS Patients

مجله دانشکده پزشکی اصفهان, 2011
Background: Multiple sclerosis and ulcerative colitis are two chronic and disabling disease that cause many problems to patients. Until now there is not a good study to determine relation and similarity between this disease.
Masood Etemadifar, Ahmad Chitsaz, Maryam Mollabashi, Azam Moradi, Mehdi Teimouri, Shirin Ashkbosi   +5 more
doaj  

HECTD1 Directs HIF‐1α to Facilitate Intestinal Inflammation and Carcinogenesis via Promoting Th17 Differentiation and Glycolysis

Advanced Science, EarlyView.
HECTD1 emerges as an upstream amplifier of Th17 metabolic programming by promoting K63‐linked ubiquitination of IGF2BP3 and enhancing HIF‐1α translation. HIF‐1α reciprocally drives HECTD1 transcription, establishing a positive regulatory loop that sustains glycolysis and Th17 differentiation.
Shuiyu Xu, Qiaoqiao Han, Feixiang Wang, Yuerong Zhang, Haoran Feng, Kun Liu, Fang Xiu Luo, Fei Yuan, Xuesong Zhao, Xiaoyan Yu, Haiyan Huang, Qiang Zou, Ren Zhao   +12 more
wiley   +1 more source

Interaction Between Operator and Assistant Certification Is Associated With Local Recurrence After Laparoscopic Rectal Cancer Surgery: An Ancillary Analysis of the EnSSURE Study

Annals of Gastroenterological Surgery, EarlyView.
A significant synergistic interaction between operator and assistant certification was associated with a lower risk of local recurrence after laparoscopic rectal cancer surgery. Patients treated by both ESSQS‐qualified operators and assistants had the lowest risk of local recurrence, whereas a single qualification alone was not associated with a ...
Yusuke Sakimura, Hiroyuki Bando, Koya Hida, Tatsunari Fukuoka, Tohru Funakoshi, Fuminori Teraishi, Kay Uehara, Yuji Inoue, Nobuaki Suzuki, Nobuki Ichikawa, Hiroaki Iijima, Akinobu Taketomi, Yoshiharu Sakai, Takeshi Naitoh, Ichiro Takemasa, the EnSSURE study group collaboratives within the Japan Society of Laparoscopic Colorectal Surgery, Akinobu Furutani, Akiyoshi Kanazawa, Akiyoshi Noda, Atsushi Ishibe, Chikayoshi Tani, Daisuke Yamamoto, Fumihiko Fujita, Fumio Ishida, Fumitaka Asahara, Heita Ozawa, Hideaki Karasawa, Hideki Osawa, Hiroaki Nagano, Hiroaki Takeshita, Hirofumi Ota, Hirokazu Suwa, Hiroki Ochiai, Hiroomi Ogawa, Hiroshi Saeki, Hirotoshi Hasegawa, Hisanaga Horie, Hisashi Nagahara, Jun Watanabe, Kaori Hayashibara, Kazuhiro Takehara, Ken Kojo, Ken Okamoto, Kenichiro Saito, Koji Ikeda, Koji Munakata, Koki Otsuka, Koki Goto, Kunihiko Nagakari, Mamoru Uemura, Manabu Shimomura, Manabu Shiozawa, Manabu Takata, Manabu Yamamoto, Masaaki Ito, Masafumi Inomata, Masahiko Watanabe, Masakatsu Numata, Masashi Miguchi, Masatsune Shibutani, Mayumi Ozawa, Mitsuhisa Takatsuki, Naoya Aisu, Naruhiko Sawada, Ryo Ikeshima, Ryo Inada, Ryuichi Oshima, Satoshi Maruyama, Shigehiro Kojima, Shigeki Yamaguchi, Shigenori Homma, Shiki Fujino, Shinichiro Mori, Shinobu Ohnuma, Sho Takeda, Shota Aoyama, Shuji Saito, Shunpei Mukai, Shusaku Takahashi, Takahiro Sasaki, Takahiro Yamanashi, Takeru Matsuda, Takuya Miura, Tatsunori Ono, Tatsuya Kinjo, Tatsuya Shonaka, Teni Godai, Tomohiro Adachi, Tomohiro Yamaguchi, Tomohisa Furuhata, Tomonori Akagi, Toshimoto Kimura, Toshisada Aiba, Toshiya Nagasaki, Toshiyoshi Fujiwara, Tsukasa Shimamura, Tsunekazu Mizushima, Yasuhito Iseki, Yasuo Sumi, Yasushi Rino, Yasuyuki Kamada, Yohei Kurose, Yoshiaki Kita, Yoshihiro Kakeji, Yoshihiro Takashima, Yoshihito Ide, Yoshinori Munemoto, Yoshito Akagi, Yoshiyuki Ishii, Yuki Kiyozumi, Yukihito Kokuba, Yukitoshi Todate, Yusuke Sakimura, Yusuke Shimodaira, Yusuke Suwa   +114 more
wiley   +1 more source

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita, Tadanobu Shimura, Mikio Kawamura, Yuhki Koike, Yuji Toiyama   +4 more
wiley   +1 more source

Lifestyle Issues in Inflammatory Bowel Disease – Smoking

Canadian Journal of Gastroenterology, 1994
During the pa t decade, smoking habit has been identified as a major exogenous factor in inflammatory bowel disease (IBD). It is associated not only with the development of the disease but al o with the clinical course in established disease.
Cecilia Benoni
doaj   +1 more source

Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To evaluate the association between preoperative neoadjuvant therapy and short‐term outcomes of transanal total mesorectal excision for rectal cancer. Methods We retrospectively analyzed patients who underwent transanal total mesorectal excision at 26 Japanese institutions between 2012 and 2019.
Takafumi Shima, Hiroki Hamamoto, Takeru Matsuda, Ichiro Takemasa, Keitaro Tanaka, Toshiki Mukai, Jun Watanabe, Sang‐Woong Lee, Seiichiro Yamamoto, Takeshi Naitoh, Ta‐Ta‐Mi Study Group Collaborators from the Japan Society of Laparoscopic Colorectal Surgery, Akihiro Kondo, Akinobu Taketomi, Akiyoshi Kanazawa, Atsushi Ogura, Chikayoshi Tani, Gunpei Yoshimatsu, Hideki Endo, Hideya Kashihara, Hirokazu Suwa, Junichiro Kawamura, Kay Uehara, Kei Kimura, Keiichi Okano, Keiichiro Okuyama, Kenji Okita, Kiyoshi Maeda, Kohei Shigeta, Koji Okabayashi, Koya Hida, Masafumi Inomata, Masahiko Watanabe, Masaji Tani, Masataka Ikeda, Masatsune Shibutani, Masayoshi Iwamoto, Masayuki Ishii, Nobuki Ichikawa, Shigenori Honma, Shinichiro Mori, Shiro Terai, Suguru Hasegawa, Takeshi Okabayashi, Takuya Tokunaga, Tatsunari Fukuoka, Tatsuya Manabe, Tatsuya Shonaka, Tomonori Akagi, Toru Kuramoto, Toru Miyake, Toshikatsu Nitta, Toshiki Mukai, Yoshihito Ide, Yosuke Fukunaga, Yuki Murata, Yukinari Tokoro, Yukitoshi Todate, Yusaku Shogen   +57 more
wiley   +1 more source