Results 151 to 160 of about 215,870 (306)

Inadequate Zinc Intake in Adolescents Aggravates Inflammatory Bowel Disease by Inhibiting Antibody Class Switch Recombination in Mucosal B Cells Through Intestinal Microbial‐Derived KMV

iMetaMed, EarlyView.
The study reveals that inadequate zinc intake disrupts gut microbiota's ability to degrade isoleucine, leading to the accumulation of metabolite KMV. KMV inhibits antibody class‐switching in mucosal B cells by suppressing the p‐ATM‐CTIP‐Hmces pathway, impairing IgA/IgG production.
Wenbo Jiang, Yiding Geng, Bai Li, Conghui Qiao, Zijie Liu, Xinyu Shan, Xinyang Wang, Wei Wei, Tianshu Han   +8 more
wiley   +1 more source

Lymph‐based liquid biopsy: Current progress and future potential

Interdisciplinary Medicine, EarlyView.
Recent evidence under the revised Starling principle indicates that lymph‐based liquid biopsies may offer superior diagnostic performance over blood‐based counterparts in certain clinical scenarios, such as early‐stage solid tumor detection. Currently, various biomarkers within the lymphatic system show significant diagnostic potential for a range of ...
Dongdong Liu, Leheng Cheng, Xiaolin Hu, Sergio Bernardini, Hong Zhang, Ling Zhu, Yang Luo   +6 more
wiley   +1 more source

GastroNet: A robust attention‐based deep learning and cosine similarity feature selection framework for gastrointestinal disease classification from endoscopic images

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Diseases of the Gastrointestinal (GI) tract significantly affect the quality of human life and have a high fatality rate. Accurate diagnosis of GI diseases plays a pivotal role in healthcare systems. However, processing large amounts of medical image data can be challenging for radiologists and other medical professionals, increasing the risk ...
Muhammad Nouman Noor, Muhammad Nazir, Imran Ashraf, Nouf Abdullah Almujally, Muhammad Aslam, Syeda Fizzah Jilani   +5 more
wiley   +1 more source

Ulcerative Colitis

International Journal of Clinical Practice, 1958
openaire   +3 more sources

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Ulcerative colitis in Nigerian children: A report of two cases and review of the literature

Nigerian Journal of Paediatrics
: Ulcerative colitis (UC) is a relapsing, idiopathic chronic inflammatory disorder of colon characterised by ulcerations of the colon with bleeding, mucosal crypt abscesses and inflammatory pseudo polyps associated with abdominal pain with tenesmus and ...
Akinyinka OO, Adepoju AA , Ashubu OF, Ogunbosi BO, Olatunji RB, Akere A, Orimadegun AE, Oluwasola AO   +7 more
doaj  

Oral rehydration solution for the management of fluid and electrolyte disturbances in patients with an ileostomy: A scoping review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Ileostomy creation is common among patients with colorectal cancer, diverticulitis, and inflammatory bowel disease. Surgical removal or diversion of the colon can result in nutrition complications, most notably dehydration—a leading cause of hospital readmission—and increased risk of kidney injury.
Austin J. Hoeg, Jessica Jaques, Remy Johnson, Megan Kocher, Alexa Weingarden, Byron Vaughn, Alexander Khoruts, Cyrus Jahansouz, Ryan T. Hurt, Levi M. Teigen   +9 more
wiley   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

Journal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar, Jeba Mercy Gnanasekaran, Niyant Ganesh, Cindy Zhou, Amy Plotkin, Giacomo Baima, Massimo Costalonga, Fenfen Zhou, Hanping Feng, Priyam Jani, Jean‐Pierre Raufman, Vivek Thumbigere‐Math   +11 more
wiley   +1 more source

Nutrition care and dietetic resources in pediatric inflammatory bowel disease: An initiative of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition Porto Group and Special Interest Group

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Dietary therapy is often used in the management of children with inflammatory bowel diseases (IBD). Nevertheless, appropriate dietetic support and resources are not universally available, potentially leading to variable practices. This survey aimed to describe contemporary dietary practices and resourcing across IBD member centers ...
Rotem Sigall Boneh, Noga Oren, Eytan Wine, Dror S. Shouval, Richard K. Russell, Javier Martín‐de‐Carpi, Konstantinos Gerasimidis   +6 more
wiley   +1 more source

Real‐world data on STRIDE‐II treatment targets in a pediatric cohort with inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives STRIDE (selecting therapeutic targets in inflammatory bowel disease) established evidence‐based targets for treat‐to‐target strategies in IBD. STRIDE‐II designates clinical remission, C‐reactive protein (CRP) normalization, and fecal calprotectin (FC) reduction as short‐ to intermediate‐term targets, and mucosal healing as a long ...
Marie‐Luise Frank, Thu Giang Le Thi, Ina Schacker, Lena Bragagna, Milena Geist, Simon Buehler, Victoria Riedl, Sibylle Koletzko, Tobias Schwerd, Hannes Hoelz   +9 more
wiley   +1 more source