Results 161 to 170 of about 114,812 (257)

Crohn's Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition). [PDF]

Biomedicines
Long D, Sung JJ.
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source

Histopathological predictor of response to mirikizumab in active ulcerative colitis. [PDF]

Clin J Gastroenterol
Horiuchi I, Horiuchi A, Horiuchi K.
europepmc   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu, Chien‐Ming Chen, Tony Kou, Tai‐Di Chen, Ming‐Jung Meng, Chen‐Wang Chang, Jen‐Wei Chou, Tien‐Yu Huang, Cheng‐Tang Chiu, Yu‐Bin Pan, Puo‐Hsien Le, Ming‐Yao Su   +11 more
wiley   +1 more source

Kangfuxin liquid enema plus adalimumab for ulcerative colitis: a retrospective cohort study. [PDF]

Am J Transl Res
Zhao M, Yu T.
europepmc   +1 more source

Pasteurella lipoprotein E interacts with host ABCF2 to facilitate adhesion and cell apoptosis

mLife, EarlyView.
Abstract Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (PlpE) of P. multocida contributed to bacterial adhesion to host cells.
Yuyao Shang, Fei Wang, Menghan Chen, Zihao Wang, Hanyuan Liu, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng   +8 more
wiley   +1 more source

Shared gene signatures and biochemical regulatory networks linking Parkinson's disease and ulcerative colitis. [PDF]

NPJ Parkinsons Dis
Sun X, An Z, Wang S, Wang K.
europepmc   +1 more source

Distinct Symptom Occurrence Subgroups Among Patients With Colorectal Cancer: Differences in Social Determinants of Health and Diet Quality

Research in Nursing &Health, EarlyView.
ABSTRACT Colorectal cancer (CRC) is a leading cause of cancer mortality in the United States. Many patients with CRC experience physical and psychological symptoms that diminish quality of life and are shaped by social determinants of health (SDOH) and diet quality.
Youran Lee, Qing Yang, Melissa Kay, Donald E. Bailey, Biljana Gigic, Sheetal Hardikar, Adetunji T. Toriola, David Shibata, Christopher I. Li, Doratha A. Byrd, Jane C. Figueiredo, Ildiko Strehli, Megan Mclaws, Vaia Florou, Mmadili Ilozumba, Patricia Erickson, Apurva Medhe, Cornelia M. Ulrich, Rosa M. Gonzalez‐Guarda   +18 more
wiley   +1 more source

The Role of Nuclear APOBEC Enzymes in Neoplastic Progression of Ulcerative Colitis. [PDF]

Clin Exp Gastroenterol
Alsøe L, Brackmann SA, Liu Y, Wennerström AB, Esbensen QY, Kalyanasundaram S, Lefol Y, Domanska D, Andersen SN, Nilsen HL.   +9 more
europepmc   +1 more source