Efficacy of upadacitinib induction for pediatric inflammatory bowel disease
Abstract Objectives Upadacitinib, a second‐generation Janus kinase (JAK) inhibitor, is approved for moderate to severe Crohn's disease (CD) and ulcerative colitis (UC) in adults. Its efficacy in pediatric patients remains unclear, though early reports suggest benefits in refractory inflammatory bowel disease (IBD).
Evan Greenhall +5 more
wiley +1 more source
Characteristics of anti-integrin αvβ6 autoantibodies in patients with ulcerative colitis. [PDF]
Takimoto I +17 more
europepmc +1 more source
Abstract Skin and lung findings, including the rare findings of leukocytoclastic vasculitis (LCV) and necrobiotic pulmonary nodules, are known extraintestinal manifestations (EIMs) of inflammatory bowel disease. However, these rare EIMs have typically been reported as being a sign of active intestinal disease.
Joshua D. Noe +3 more
wiley +1 more source
Discrepancies between patients' and gastroenterologists' perceptions of diagnosis and treatment in ulcerative colitis: a multicenter retrospective study. [PDF]
Fan Z +19 more
europepmc +1 more source
Postoperative Weight Gain, Due to Fluid Retention After Ovarian Cancer Surgery—How Much Is too Much?
ABSTRACT Background and Objectives Postoperative complications after cytoreductive surgery in ovarian cancer patients are associated with impaired survival. Here, we investigated the association between postoperative weight gain due to fluid retention and the development of complications and anastomotic leakage (AL).
Eva K. Egger +7 more
wiley +1 more source
Mechanism of Morbidity Based on Ulcerative Colitis: A Review of Traditional Chinese Medicine Treatment of Ulcerative Colitis. [PDF]
Huang Y, Ma Z, Xu X, Liu Z.
europepmc +1 more source
Effect of Systemic Immunomodulators on Incidence of Alopecia Areata: A Retrospective Cohort Study
ABSTRACT Background Alopecia areata (AA) is a chronic autoimmune hair loss disorder. Patients with primary autoimmune diseases commonly use systemic immunomodulators to manage disease and have an increased risk of developing AA. Systemic immunomodulators have diverse immunologic effects, but their impact on AA risk is not well understood. Objectives We
Angela Rose Liu +2 more
wiley +1 more source
Regional and Sex-Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis. [PDF]
Tshikudi DM +6 more
europepmc +1 more source
Defensins and Efflux Transporters Meet Their Fate in 2008: No Major Role in the Pathogenesis of Inflammatory Bowel Disease [PDF]
Ochsenkühn, Thomas
core +1 more source
Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru +13 more
wiley +1 more source

