Ulcerative Colitis-Diagnostic and Therapeutic Algorithms.
BACKGROUND Ulcerative colitis is a chronic inflammatory bowel disease with an estimated 150 000 patients in Germany alone. METHODS This review is based on publications about current diagnostic and therapeutic strategies for ulcerative colitis that were
T. Kucharzik+3 more
semanticscholar +1 more source
Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Folwaczny, Christian+5 more
core +1 more source
Infliximab for induction and maintenance therapy for ulcerative colitis.
BACKGROUND Infliximab, a chimeric monoclonal antibody directed against tumor necrosis factor alpha, is an established treatment for Crohn's disease but not ulcerative colitis. METHODS Two randomized, double-blind, placebo-controlled studies--the Active
P. Rutgeerts+13 more
semanticscholar +1 more source
Probiotics for maintenance of remission in ulcerative colitis.
BACKGROUND Ulcerative colitis is an inflammatory condition affecting the colon, with an annual incidence of approximately 10 to 20 per 100,000 people. The majority of people with ulcerative colitis can be put into remission, leaving a group who do not ...
Zipporah Iheozor-Ejiofor+5 more
semanticscholar +1 more source
Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
core +1 more source
Causation of human ulcerative colitis: A lead from an animal model that mirrors human disease
Most models of experimental colitis do not replicate human ulcerative colitis and do not help in defining the causation of human ulcerative colitis. Inducing pantothenic acid deficiency in pigs produces an ideal model in terms of extent, histology, and ...
William E W Roediger
doaj +1 more source
Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice
Background/Aims: Deoxyschizandrin as one of the most important component of Schisandra chinensis (Turcz.) Baill plays an immunomodulatory role in a variety of diseases, yet its role in ulcerative colitis remains to be elucidated.
Wen-feng Zhang+6 more
doaj +1 more source
A case of pemphigus vulgaris associated with ulcerative colitis [PDF]
Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel disease.
Joo Wan Seo+8 more
doaj +1 more source
Ulcerative colitis: understanding its cellular pathology could provide insights into novel therapies
Dynamic interactions between the gastrointestinal epithelium and the mucosal immune system normally contribute to ensuring intestinal homeostasis and optimal immunosurveillance, but destabilisation of these interactions in genetically predisposed ...
Amandip Kaur, P. Goggolidou
semanticscholar +1 more source
Prevalence of Entamoeba Histolytica infection in patients with colitis (Ulcerative and Infective)
Background: Ulcerative colitis (UC) is a chronic inflammatory disorder of the colon that often extends to involve the remainder of the large intestine in a continuous manner. Intestinal amoebiasis can present as a chronic, dysenteric syndrome of diarrhea,
Luay I. Farhan Al-Rwi+2 more
doaj +1 more source