Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou +31 more
core +1 more source
ACG Clinical Guideline: Ulcerative Colitis in Adults
Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and represent the official practice recommendations of the American College of Gastroenterology.
D. Rubin +4 more
semanticscholar +1 more source
CD3+CD4+LAP+Foxp3-regulatory cells of the colonic lamina propria limit disease extension in ulcerative colitis [PDF]
Background and Aims: In ulcerative colitis (UC), inflammation begins in the rectum and can extend proximally throughout the entire colon. The extension of inflammation is an important determinant of disease course, and may be limited by the action of ...
Amendola, Antonello +10 more
core +3 more sources
Systemic inflammation in pre-clinical ulcerative colitis.
BACKGROUND AND AIM Pre-clinical ulcerative colitis is poorly defined. We aimed to characterize the pre-clinical systemic inflammation in ulcerative colitis, using a comprehensive set of proteins.
D. Bergemalm +54 more
semanticscholar +1 more source
Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]
The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico +5 more
core +1 more source
Identification of an Anti-Integrin αvβ6 Autoantibody in Patients with Ulcerative Colitis.
BACKGROUND AND AIMS Ulcerative colitis is the most frequent type of inflammatory bowel disease and is characterized by colonic epithelial cell damage. Although involvement of autoimmunity has been suggested in ulcerative colitis, specific autoantigens ...
T. Kuwada +27 more
semanticscholar +1 more source
Associations between an gene polymorphism and ulcerative colitis by ARMS-PCR [PDF]
Ulcerative colitis is a form of inflammatory bowel disease characterized by chronic inflammation of the colon and rectum. The abnormal lesions in the digestive system caused by ulcerative colitis and intermittent colitis are of major clinical importance.
Mahsa Sadat Hashemi Doulabi +2 more
doaj +1 more source
Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
core +2 more sources
Single-cell sequencing analyses reveal changes in B and T cell transcriptional states in the context of ulcerative colitis. Profiles of rogue gut lymphocytes Dysregulated human gut B and T lymphocytes contribute to the immunopathogenesis of ulcerative ...
B. Boland +29 more
semanticscholar +1 more source
Causation of human ulcerative colitis: A lead from an animal model that mirrors human disease
Most models of experimental colitis do not replicate human ulcerative colitis and do not help in defining the causation of human ulcerative colitis. Inducing pantothenic acid deficiency in pigs produces an ideal model in terms of extent, histology, and ...
William E W Roediger
doaj +1 more source

