Results 51 to 60 of about 208,146 (286)

Molecular Changes in the Non-Inflamed Terminal Ileum of Patients with Ulcerative Colitis

Cells, 2020
Ulcerative colitis is a chronic inflammatory disease confined to the colon. Although the etiopathogenesis remains unknown, small bowel dysfunctions like histological and permeability alterations have been described in ulcerative colitis. We evaluated the
Ho-Su Lee, Maaike Vancamelbeke, Sare Verstockt, Tom Wilms, Bram Verstockt, João Sabino, Marc Ferrante, Séverine Vermeire, Isabelle Cleynen   +8 more
doaj   +1 more source

A Case of Ulcerative Colitis with Stenosing Symptoms Caused by Localized Giant Inflammatory Polyposis [PDF]

, 2021
A 40-year-old man with relapsed ulcerative colitis（UC）underwent colonoscopy. Colonoscopy revealed a dense cluster of elongated polyps with surrounding ulcerative lesions in the ascending colon and intestinal stricture at the same site.
Nakamura, Takatoshi, Ishida, Kazuyuki, Abe, Keiichiro, Ihara, Keisuke, Watanabe, Shoko, Goda, Kenichi, Kashima, Ken, Tominaga, Keiichi, Taratani, Nasuka, Tanaka, Takanao, Kanamori, Akira, Kanazawa, Mimari, Irisawa, Atsushi, Ishikawa, Manabu, Yamaguchi, Shintaro   +14 more
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Vancomycin Therapy for Induction and Maintenance of Remission in a Patient with Refractory Ulcerative Colitis and Primary Sclerosing Cholangitis: A Case Report and Literature Review

Case Reports in Gastroenterology
Introduction: Ulcerative colitis is a chronic inflammatory bowel disease that affects the colon. About 5% of ulcerative colitis patients also present with primary sclerosing cholangitis, a chronic inflammatory disease marked by cholestasis and
Naama Lang, Yana Davidov, Tomer Hoffman, Sivan Harnik, Abraham Rami Eliakim, Shomron Ben-Horin, Bella Ungar   +6 more
doaj   +1 more source

New Diagnostic Possibilities for Determining the Activity of Ulcerative Colitis: The Role of Neutrophils

Архивъ внутренней медицины, 2022
The incidence of ulcerative colitis has been increasing in recent years, and its manifestation at a young age has become a trend that is prognostically unfavorable.
E. V. Bolotova, K. A. Yumukyan, A. V. Dudnikova   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Clinical practice and outcome of patients with elderly‐onset ulcerative colitis: Insights from a nationwide claims database study in Japan

JGH Open
Background and Aim The number of older patients with ulcerative colitis is increasing; however, limited data exist regarding the differences between elderly‐ and non‐elderly‐onset ulcerative colitis.
Rintaro Moroi, Yoichi Kakuta, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

Oral Nanomicelle-Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment. [PDF]

Adv Sci (Weinh)
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Xin F, Xie Z, Zhao D, Yang L, Wan Y, Liu Z, Xiong S, Zhang Y, Feng L, Wan H.   +9 more
europepmc   +2 more sources

Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal Escherichia coli [PDF]

, 2009
BACKGROUND: Historically, histiocytic ulcerative (HUC) (or granulomatous) colitis of Boxer dogs was considered an idiopathic immune-mediated disease with a poor prognosis. Recent reports of dramatic responses to enrofloxacin and the discovery of invasive
Dogan, B., Nicholls, P.K., Simpson, K.W., Davies, D.R., James, F.E., MacDonough, S.P., Mansfield, C.S., Craven, M., O'Hara, A.J.   +8 more
core  

The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. [PDF]

, 2010
Recent evidence suggests a crucial role of the endocannabinoid system, including the cannabinoid 1 receptor (CNR1), in intestinal inflammation. We therefore investigated the influence of the CNR1 1359 G/A (p.Thr453Thr; rs1049353) single nucleotide ...
Brand, Stephan, Burkhard Göke, Göke, Burkhard, Storr, Martin, Göke Burkhard, Ochsenkühn, Thomas, Stephan Brand, Brand Stephan, Thomas Ochsenkühn, Storr Martin, Pfennig, Simone, Dominik Emmerdinger, Peter Lohse, Martin Storr, Emmerdinger Dominik, Diegelmann, Julia, Lohse, Peter, Simone Pfennig, Diegelmann Julia, Emmerdinger, Dominik, Julia Diegelmann, Ochsenkühn Thomas, Lohse Peter, Pfennig Simone   +23 more
core   +1 more source