Comparative study of under-expressed prognostic biomarkers and pivotal signaling pathways in colon cancer and ulcerative colitis using integrated bioinformatics approach [PDF]
arXiv, 2023 Colon cancer is a prevalent gastrointestinal malignancy arising in the colon. Ulcerative colitis(UC) is one of the risk factors of colorectal cancer. The detection of under-expressed biomarkers and molecular mechanisms in UC and colon cancer can lead to effective management of colitis-associated cancer. A total of two mRNA expression datasets (GSE87473
arxiv
CD3+CD4+LAP+Foxp3-regulatory cells of the colonic lamina propria limit disease extension in ulcerative colitis [PDF]
, 2018 Background and Aims: In ulcerative colitis (UC), inflammation begins in the rectum and can extend proximally throughout the entire colon. The extension of inflammation is an important determinant of disease course, and may be limited by the action of ...
Amendola, Antonello +10 more
core +3 more sources
Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]
, 2016 The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico +5 more
core +1 more source
Class Distance Weighted Cross-Entropy Loss for Ulcerative Colitis Severity Estimation [PDF]
arXiv, 2022 In scoring systems used to measure the endoscopic activity of ulcerative colitis, such as Mayo endoscopic score or Ulcerative Colitis Endoscopic Index Severity, levels increase with severity of the disease activity. Such relative ranking among the scores makes it an ordinal regression problem.
arxiv
Ustekinumab as Induction and Maintenance Therapy for Ulcerative Colitis.
New England Journal of Medicine, 2019 BACKGROUND The efficacy of ustekinumab, an antagonist of the p40 subunit of interleukin-12 and interleukin-23, as induction and maintenance therapy in patients with ulcerative colitis is unknown.
B. Sands +15 more
semanticscholar +1 more source
Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up study [PDF]
, 2003 AIM: IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.
Balogh, Zsuzsanna +6 more
core +1 more source
Two for One: Coexisting Ulcerative Colitis and Crohn’s Disease
Canadian Journal of Gastroenterology, 2002 Three cases of coexisting ulcerative colitis and Crohn’s disease are presented. In the first case, the patient had a long-standing history of ulcerative proctitis before developing Crohn’s colitis.
Grant I Chen +2 more
doaj +1 more source
Ulcerative colitis: nutritional habits as the disease risk factor
Russian Open Medical Journal, 2021 Background — Ulcerative colitis results from a complex interaction between genetic, internal (intestinal microflora) and external (environment) factors.
Galiya R. Bikbavova +4 more
doaj +1 more source
Vedolizumab versus Adalimumab for Moderate-to-Severe Ulcerative Colitis.
New England Journal of Medicine, 2019 BACKGROUND Biologic therapies are widely used in patients with ulcerative colitis. Head-to-head trials of these therapies in patients with inflammatory bowel disease are lacking.
B. Sands +12 more
semanticscholar +1 more source
Budesonide Foam Has a Favorable Safety Profile for Inducing Remission in Mild-to-Moderate Ulcerative Proctitis or Proctosigmoiditis. [PDF]
, 2015 BackgroundBudesonide foam, a rectally administered, second-generation corticosteroid with extensive hepatic first-pass metabolism, is efficacious for the treatment of mild-to-moderate ulcerative proctitis and ulcerative proctosigmoiditis.AimThe aim of ...
Barrett, Andrew C +10 more
core +3 more sources