On the Evaluation of Surrogate Markers in Real World Data Settings [PDF]
arXiv, 2021 Shortcomings of randomized clinical trials are pronounced in urgent health crises, when rapid identification of effective treatments is critical. Leveraging short-term surrogates in real-world data (RWD) can guide policymakers evaluating new treatments.
arxiv
ULCERATIVE COLITIS IN CHILDREN [PDF]
Romanian Journal of Pediatrics, 2009 Chronic nonspecific ulcerative colitis remaine a disease of unkown etiology, although much new information continues to be gleaned from basic research and clinical trials. In most instances, ulcerative colitis respond to medical therapy.
Florea Iordăchescu
doaj +1 more source
Deep Bayesian Active-Learning-to-Rank for Endoscopic Image Data [PDF]
arXiv, 2022 Automatic image-based disease severity estimation generally uses discrete (i.e., quantized) severity labels. Annotating discrete labels is often difficult due to the images with ambiguous severity. An easier alternative is to use relative annotation, which compares the severity level between image pairs.
arxiv
Fecal calprotectin is a useful marker to diagnose ulcerative colitis from irritable bowel syndrome
Advanced Biomedical Research, 2015 Background: This study was aimed to evaluate the predictive value of fecal calprotectin in patients with ulcerative colitis from patients with irritable bowel syndrome (IBS).
Hamid Kalantari +2 more
doaj +1 more source
Disease Severity Regression with Continuous Data Augmentation [PDF]
arXiv, 2023 Disease severity regression by a convolutional neural network (CNN) for medical images requires a sufficient number of image samples labeled with severity levels. Conditional generative adversarial network (cGAN)-based data augmentation (DA) is a possible solution, but it encounters two issues.
arxiv
Integrative computational approach identifies immune‐relevant biomarkers in ulcerative colitis
FEBS Open Bio, 2022 Ulcerative colitis is a common inflammatory bowel disease with a complex genetic and immune etiology. Immune infiltration plays a vital role in the development of ulcerative colitis.
Tianzhen He +9 more
doaj +1 more source
Gastrointestinal Mucosal Problems Classification with Deep Learning [PDF]
arXiv, 2023 Gastrointestinal mucosal changes can cause cancers after some years and early diagnosing them can be very useful to prevent cancers and early treatment. In this article, 8 classes of mucosal changes and anatomical landmarks including Polyps, Ulcerative Colitis, Esophagitis, Normal Z-Line, Normal Pylorus, Normal Cecum, Dyed Lifted Polyps, and Dyed ...
arxiv
DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
, 2014 Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Bronsky, Jiri +10 more
core +2 more sources
Combined Hepatic and Splenic Abscesses in a Patient with Ulcerative Colitis [PDF]
, 2007 Liver abscesses are very rare complications of ulcerative colitis, and furthermore, there has been only one case of splenic abscess in a patient with ulcerative colitis reported in the English literature. We recently encountered a patient with ulcerative
Andre +27 more
core +2 more sources
Histologic Features with Predictive Value for Outcome of Patients with Ulcerative Colitis [PDF]
, 2017 Ulcerative colitis is an inflammatory bowel disease with variable evolution, in which is difficult to establish patient’s outcome. Histology is an important part of diagnosis of ulcerative colitis and has an increasing role in patients’ management, since
Mateescu, Radu Bogdan, Popp, Cristiana
core +2 more sources