Results 61 to 70 of about 215,870 (306)

Clinical practice and outcome of patients with elderly‐onset ulcerative colitis: Insights from a nationwide claims database study in Japan

JGH Open
Background and Aim The number of older patients with ulcerative colitis is increasing; however, limited data exist regarding the differences between elderly‐ and non‐elderly‐onset ulcerative colitis.
Rintaro Moroi, Yoichi Kakuta, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

A Parasite That Should not be Neglected in Patients with Ulcerative Colitis: Entamoeba histolytica

Türkiye Parazitoloji Dergisi
Objective: To determine the prevalence of amoebiasis, which has been neglected in recent years according to the World Health Organization, in ulcerative colitis patients and investigate the relationship between amoebiasis and ulcerative colitis. Methods:
Murat Soylu, Abdurrahman Ekici, Selahattin Aydemir, Şehriban Yürektürk, Önder Akkaş   +4 more
doaj   +1 more source

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker, Dilbarova, Rima, Gilligan, John, Hoxha, Kevther, Kossenkov, Andrew, Mullin, James M., Prendergast, George C., Thomas, Sunil, Whittaker, Kelly   +8 more
core   +2 more sources

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Ulcerative colitis: focus on colonic mucosal resistance

Бюллетень сибирской медицины, 2022
In recent decades, following cooperation between scientists in various specialties, new unique data on the pathogenesis of ulcerative colitis have been obtained.
M. A. Livzan, G. R. Bicbavova, A. E. Romanyuk   +2 more
doaj   +1 more source

Restorative proctocolectomy with ileal pouch reservoir in ulcerative colitis : the first series from Malta [PDF]

, 1991
Seventy five to eighty percent of patients with ulcerative colitis are more or less satisfactorily treated medically. Surgery cures the disease, but because proper surgical therapy has until recently necessitated a permanent ileostomy, physicians and ...
Gatt, Dennis
core  

PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. [PDF]

, 2012
Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel disease (
Achkar, Jean-Paul, Balschun, Tobias, Brand, Stephan, Czamara, Darina, Diegelmann, Julia, Duerr, Richard H., Franke, Andre, Glas, Jürgen, Kamboh, M. Ilyas, Müller-Myhsok, Bertram, Olszak, Torsten, Pasciuto, Giulia, Seiderer, Julia, Wetzke, Martin, Wolf, Christiane   +14 more
core   +4 more sources

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source