Results 71 to 80 of about 269,130 (350)

A Parasite That Should not be Neglected in Patients with Ulcerative Colitis: Entamoeba histolytica

Türkiye Parazitoloji Dergisi
Objective: To determine the prevalence of amoebiasis, which has been neglected in recent years according to the World Health Organization, in ulcerative colitis patients and investigate the relationship between amoebiasis and ulcerative colitis. Methods:
Murat Soylu, Abdurrahman Ekici, Selahattin Aydemir, Şehriban Yürektürk, Önder Akkaş   +4 more
doaj   +1 more source

Histopathological evaluation of ulcerative colitis in colonoscopic biopsies

Journal of Pathology of Nepal, 2016
Background: Histopathologic evaluation of colonoscopic mucosal biopsy remains one of the earliest modalities of investigation in patients clinically suspected of ulcerative colitis. Pathologists should be aware of classical histomorphological features to
R Dhakhwa, HG Shrestha, IL Acharya
doaj   +1 more source

Assessment of Circulating MicroRNAs for the Diagnosis and Disease Activity Evaluation in Patients with Ulcerative Colitis by Using the Nanostring Technology [PDF]

, 2015
Background: Clinical decision and patient care management in inflammatory bowel diseases is largely based on the assessment of clinical symptoms, while the biomarkers currently in use poorly reflect the actual disease activity.
Alexandra Touroutoglou, Angelos Oikonomopoulos, Baltimore, Baumgart, Cho, Christos Polytarchou, CramaBohbouth, Creemers, Daniel W. Hommes, Dimitrios Iliopoulos, Georgios Koukos, Guo, Hatziapostolou, Iskandar, Kappelman, Kosaka, Kumar, Lewis, Linskens, Loftus, Mitchell, Pepys, Saverymuttu, Schoepfer, Schroeder, Schwarzenbach, Solem, Solem, Swapna Mahurkar, van Rooij, Wang, Xavier   +31 more
core   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Clinical practice and outcome of patients with elderly‐onset ulcerative colitis: Insights from a nationwide claims database study in Japan

JGH Open
Background and Aim The number of older patients with ulcerative colitis is increasing; however, limited data exist regarding the differences between elderly‐ and non‐elderly‐onset ulcerative colitis.
Rintaro Moroi, Yoichi Kakuta, Hiroshi Nagai, Yusuke Shimoyama, Takeo Naito, Hisashi Shiga, Yoshitaka Kinouchi, Atsushi Masamune   +7 more
doaj   +1 more source

Ulcerative colitis: focus on colonic mucosal resistance

Бюллетень сибирской медицины, 2022
In recent decades, following cooperation between scientists in various specialties, new unique data on the pathogenesis of ulcerative colitis have been obtained.
M. A. Livzan, G. R. Bicbavova, A. E. Romanyuk   +2 more
doaj   +1 more source

Intestinal barrier tightening by a cell-penetrating antibody to Bin1, a candidate target for immunotherapy of ulcerative colitis. [PDF]

, 2018
Patients afflicted with ulcerative colitis (UC) are at increased risk of colorectal cancer. While its causes are not fully understood, UC is associated with defects in colonic epithelial barriers that sustain inflammation of the colon mucosa caused by ...
Alexander, Walker, Dilbarova, Rima, Gilligan, John, Hoxha, Kevther, Kossenkov, Andrew, Mullin, James M., Prendergast, George C., Thomas, Sunil, Whittaker, Kelly   +8 more
core   +2 more sources

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Clinical Value of Fecal Calprotectin in Predicting Mucosal Healing in Patients With Ulcerative Colitis [PDF]

, 2021
Fang Chen, Yue Hu, Yihong Fan, Bin Lv
openalex   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source