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Ulipristal acetate for emergency contraception.

Australian prescriber
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Ulipristal acetate for emergency contraception

Drugs of Today, 2010
Ulipristal acetate is a progesterone receptor modulator. As an emergency contraceptive, a 30-mg micronized formulation is effective for use up to 120 h from unprotected sexual intercourse. Ulipristal acetate acts as an antagonist of the progesterone receptor at the transcriptional level and a competitive antagonist of glucocorticoid receptor function ...
J A, Russo, M D, Creinin
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Ulipristal Acetate: Contraceptive or Contragestive?

Annals of Pharmacotherapy, 2011
Ulipristal acetate is the first selective progesterone receptor modulator approved for postcoital contraception in the US. It appears to be significantly more effective in inhibition of ovulation than other forms of emergency contraception. However, ulipristal acetate is structurally similar to mifepristone, and several lines of evidence suggest that a
Jeffrey A Keenan
exaly   +3 more sources

Ulipristal Acetate for Emergency Contraception

Annals of Pharmacotherapy, 2011
OBJECTIVE: To review the pharmacology, pharmacokinetics, efficacy, and safety of data of ulipristal acetate, a new emergency contraceptive approved for use up to 120 hours after unprotected intercourse. DATA SOURCES: Articles ...
Sara E, Snow, Stephanie N, Melillo, Courtney I, Jarvis   +2 more
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Ulipristal Acetate Prior to Surgery for Endometriosis

Reproductive Sciences, 2020
Selective progesterone receptor modulators may have a role in the treatment of endometriosis. The aim of this report is to review the effect of ulipristal acetate (UPA) on endometriosis lesions and symptoms in women treated prior to surgery. A pathology review of eutopic endometrium and endometriotic lesions was conducted by two gynecologic ...
Sukhbir S, Singh, Devon, Evans, Shannen, McDonald, Mary, Senterman, Sarah, Strickland   +4 more
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Ulipristal Acetate

Drugs, 2012
Ulipristal acetate, a selective progesterone-receptor modulator, inhibits the proliferation and induces apoptosis of leiomyoma cells in vitro. It also modulates the expression of vascular endothelial growth factors and hormone receptors and modulates extracellular matrix breakdown in leiomyoma cells but not in myometrial cells.
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Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate

Revista de Chimie, 2018
Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Its main functions are playing a key role in the development, differentiation, and normal functioning of female reproduction-related target tissues including the uterus (endometrium and myometrium)
Liana Ples, Cringu Ionescu, Mihai Dimitriu, Anca Lesnic, Zorela Adriana Sgarbura, Alina Calin   +5 more
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Ulipristal Acetate

Drugs, 2011
Ulipristal acetate (ellaOne®; ella®) is the first of a new class of selective progesterone receptor modulators, and is indicated for emergency contraception within 120 hours after unprotected sexual intercourse or contraceptive failure. The principal effect of ulipristal acetate is to inhibit or delay ovulation.
Kate, McKeage, Jamie D, Croxtall
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Ulipristal Acetate for Disseminated Peritoneal Leiomyomatosis

Obstetrics & Gynecology, 2019
BACKGROUND: Disseminated peritoneal leiomyomatosis is a rare condition manifesting as hormone-sensitive soft tissue nodules lining the peritoneal cavity. Given the extensiveness of this disease, surgical management is challenging, making hormonal suppression the primary treatment. CASE:
Samantha, Benlolo, Jessica, Papillon-Smith, Ally, Murji   +2 more
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