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Effect of exposure to ulipristal acetate on sperm function
The European Journal of Contraception & Reproductive Health Care, 2012A pill containing ulipristal acetate (UPA) is used for emergency contraception (EC). Considering that, following its intake, spermatozoa may be exposed to UPA in the female genital tract we intended to evaluate sperm functions after incubation with this compound.Motile spermatozoa were selected by swim-up and were incubated under capacitating ...
María José, Munuce +5 more
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Ulipristal acetate (Esmya): restrictions on use
Drug and Therapeutics Bulletin, 2018Safety alert: Esmya (ulipristal acetate) for symptoms of uterine fibroids: restrictions to use and requirement to check liver function before, during and after treatment.1,2
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A new and efficient method for the synthesis of Ulipristal acetate
Steroids, 2014In this study, we describe another new and efficient route for preparing Ulipristal acetate. The 1,4-addition compound 5 was greatly improved after the starting material ketone 1 was underwent epoxidation, cyanation, hydroxyl group protection and Grignard addition.
Xu, Cheng +5 more
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Ulipristal acetate in emergency contraception: mechanism of action
Trends in Pharmacological Sciences, 2013We would like to discuss the mechanism of action of ulipristal acetate (UPA, marketed as ellaOne®), an orally active selective progesterone receptor modulator (SPRM) licensed for emergency contraception (EC). Each tablet contains micronized UPA 30 mg (equivalent to unmicronized UPA 50 mg) [1] and it is effective up to 120 h after unprotected ...
MOZZANEGA, BRUNO +2 more
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Pseudo-Meig's Syndrome in a Woman on Ulipristal Acetate
Journal of Obstetrics and Gynaecology Canada, 2015Ultrasound and MRI demonstrated persistent uterine enlargement with new onset of ascites. Paracentesis yielded 3.5 litres of benign serous fluid. Laparotomy revealed a 19 × 14 × 10 cm soft, deep-red oblong pedunculated fundal mass (Figure) and six intramural or subserosal fibroids from 2 to 7.5 cm in diameter.
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Long-term treatment of uterine fibroids with ulipristal acetate☆
Fertility and Sterility, 2014Philippe Bouchard +2 more
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