Results 151 to 160 of about 243,892 (195)
First series of 18 pregnancies after ulipristal acetate treatment for uterine fibroids
Fertility and Sterility, 2014 OBJECTIVE: To study the pregnancy rate after ulipristal acetate (UPA) therapy for fibroids. DESIGN: Retrospective analysis of a series of 52 patients prospectively included in the PGL4001 (ulipristal acetate) Efficacy Assessment in Reduction of Symptoms ...
Mathieu Luyckx +1 more
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Drugs, 2012
Ulipristal acetate, a selective progesterone-receptor modulator, inhibits the proliferation and induces apoptosis of leiomyoma cells in vitro. It also modulates the expression of vascular endothelial growth factors and hormone receptors and modulates extracellular matrix breakdown in leiomyoma cells but not in myometrial cells.
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Ulipristal acetate, a selective progesterone-receptor modulator, inhibits the proliferation and induces apoptosis of leiomyoma cells in vitro. It also modulates the expression of vascular endothelial growth factors and hormone receptors and modulates extracellular matrix breakdown in leiomyoma cells but not in myometrial cells.
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Ulipristal Acetate Prior to Surgery for Endometriosis
Reproductive Sciences, 2020Selective progesterone receptor modulators may have a role in the treatment of endometriosis. The aim of this report is to review the effect of ulipristal acetate (UPA) on endometriosis lesions and symptoms in women treated prior to surgery. A pathology review of eutopic endometrium and endometriotic lesions was conducted by two gynecologic ...
Sukhbir S, Singh +4 more
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Drugs, 2011
Ulipristal acetate (ellaOne®; ella®) is the first of a new class of selective progesterone receptor modulators, and is indicated for emergency contraception within 120 hours after unprotected sexual intercourse or contraceptive failure. The principal effect of ulipristal acetate is to inhibit or delay ovulation.
Kate, McKeage, Jamie D, Croxtall
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Ulipristal acetate (ellaOne®; ella®) is the first of a new class of selective progesterone receptor modulators, and is indicated for emergency contraception within 120 hours after unprotected sexual intercourse or contraceptive failure. The principal effect of ulipristal acetate is to inhibit or delay ovulation.
Kate, McKeage, Jamie D, Croxtall
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Is Ulipristal Acetate a Liver Toxic Biomolecule? Toxicity assessment of ulipristal acetate
Revista de Chimie, 2018Progesterone is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Its main functions are playing a key role in the development, differentiation, and normal functioning of female reproduction-related target tissues including the uterus (endometrium and myometrium)
Liana Ples +5 more
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Ulipristal Acetate for Disseminated Peritoneal Leiomyomatosis
Obstetrics & Gynecology, 2019BACKGROUND: Disseminated peritoneal leiomyomatosis is a rare condition manifesting as hormone-sensitive soft tissue nodules lining the peritoneal cavity. Given the extensiveness of this disease, surgical management is challenging, making hormonal suppression the primary treatment. CASE:
Samantha, Benlolo +2 more
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Ulipristal acetate as an emergency contraceptive agent
Expert Opinion on Pharmacotherapy, 2012Emergency contraceptive agents play a crucial role in preventing unplanned pregnancy. These agents and devices have been studied since the 1960s and have had varied results in terms of side effects and efficacy. A new oral tablet for emergency contraception (EC), ulipristal acetate (UPA) , is a selective progesterone receptor modulator and can be used ...
Alan M, Martinez, Michael A, Thomas
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Ulipristal acetate: a new emergency contraceptive
Expert Review of Clinical Pharmacology, 2011Ulipristal acetate (UPA) is a newly developed emergency contraceptive currently available in the USA and Europe. It is approved as a 30 mg one-time dose taken within 120 h (5 days) of unprotected intercourse or failed contraception. This selective progesterone receptor modulator appears to be more effective than the levonorgestrel-containing emergency ...
Jade L, Sullivan, Marilyn N, Bulloch
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Ulipristal Acetate: The Newest Emergency Contraceptive
Nursing for Women's Health, 2012More than 50 percent of pregnancies in the United States are unplanned. Emergency contraception has been shown to possibly reduce the risk of pregnancy by as much as 75 percent. Ulipristal acetate is a selective progesterone receptor modulator that was approved by the U.S.
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Ulipristal Acetate: A Review in Symptomatic Uterine Fibroids
Drugs, 2017Oral ulipristal acetate (Esmya®; Fibristal®), a synthetic selective progesterone receptor modulator, is the first selective progesterone modulator to be approved for the treatment of uterine fibroids. It was initially approved for the preoperative treatment of moderate to severe uterine fibroid symptoms in women of reproductive age.
Karly P, Garnock-Jones, Sean T, Duggan
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