Results 11 to 20 of about 2,785 (177)

The Concise Guide to PHARMACOLOGY 2023/24: Nuclear hormone receptors

British Journal of Pharmacology, Volume 180, Issue S2, Page S223-S240, October 2023., 2023
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and nearly 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander, John A. Cidlowski, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Laurel Coons, Peter J. Fuller, Kenneth S. Korach, Morag J. Young   +13 more
wiley   +1 more source

Assessment of the safe and efficacious dose of the selective progesterone receptor modulator vilaprisan for the treatment of patients with uterine fibroids by exposure–response modelling and simulation

British Journal of Clinical Pharmacology, Volume 88, Issue 2, Page 734-741, February 2022., 2022
Aims We report population pharmacokinetic (popPK) and exposure–response (E–R) analyses for efficacy (induced amenorrhoea [IA]) and safety (unbound oestradiol [E2] concentrations) of the selective progesterone receptor modulator vilaprisan. Results were used to inform the dose for the Phase 3 programme in patients with uterine fibroids.
Gabriele Sutter, Matthias Frei, Marcus‐Hillert Schultze‐Mosgau, Kathrin Petersdorf, Christian Seitz, Bart A. Ploeger   +5 more
wiley   +1 more source

Ulipristal acetate emergency contraception [PDF]

Journal of Family Planning and Reproductive Health Care, 2013
I read with interest the letter by Webb et al. 1 about the pitfalls of adapting the Clinical Effectiveness Unit's guidance on emergency contraception (EC).2 Their letter discusses, in relation …
openaire   +2 more sources

Treating symptomatic uterine fibroids with myomectomy: current practice and views of UK consultants [PDF]

, 2017
Background: The demand for uterus-sparing treatments is increasing as more women postpone childbirth to their 30–40s, when fibroids are more symptomatic.
A Lethaby, A Taylor, Anna Maria Belli, C Cook, C Farquhar, CD Delnevo, D Schlesinger, DD Baird, EA Stewart, ED Levens, Isaac T. Manyonda, J Donnez, J Donnez, JH Ravina, JM Sancho, L Schmidt, LM Marshall, N Al-Shabibi, R. Fusun Sirkeci, S Chudnoff, S Gizzo, S Gupta, S Okolo, SK Laughlin, The Royal College of Obstetricians and Gynaecologists and The Royal College of Radiologists, V Talaulikar   +25 more
core   +1 more source

The Effect of Ulipristal Acetate on Surgical Endometriosis Created in Rats [PDF]

, 2022
Amaç: Ulipristal Asetat'ın ratlarda oluşturulan endometriozis odakları üzerindeki etkisinin araştırılması hedeflendi. Gereç ve Yöntem: Çalışma, yaklaşık 280 gram ağırlığında 12 haftalık ratlarla yürütüldü.
Demir, Bülent, Duran, Mehmet Nuri, Kılınç, Nihal, Şahin, Hacı Öztürk   +3 more
core   +1 more source

Medical Therapies for Uterine Fibroids - A Systematic Review and Network Meta-Analysis of Randomised Controlled Trials [PDF]

, 2016
BACKGROUND: Uterine fibroids are common, often symptomatic and a third of women need repeated time off work. Consequently 25% to 50% of women with fibroids receive surgical treatment, namely myomectomy or hysterectomy.
A Armstrong, A Daniels, A Golan, A Lethaby, A Lieto, A Zimmermann, AJ Audebert, AJ Friedman, AJ Friedman, AJ Friedman, AJ Friedman, Andrew Horne, AR Williams, AR Williams, B Kroon, BJ Borah, CC Coddington, D De Aloysio, D Mavrelos, D Moher, DD Baird, DD Baird, E Roshdy, E Verspyck, E Zullo, ED Levens, EE Marsh, EK Arleo, EP Morris, ERC, A.D. Cardozo, F Parazzini, F Polatti, F Zullo, F Zullo, G Levy, G Orsini, G Salanti, GH Guyatt, GH Sayed, GS Carls, H Song, HH Bustos Lopez, Ian S. Fraser, J Balasch, J Donnez, J Donnez, J Donnez, J Gerris, J Higgins, J van de Ven, J van de Ven, J Wilkens, JB Engel, Jessica Vaughan, JH Segars, JL Esteve, JL Rutgers, K Chwalisz, K Fiscella, K Puri, KR Hodges, Kurinchi S. Gurusamy, L Deng, L Fedele, L Fedele, L Fedele, L Muzii, Lawrence M. J. Best, LJ Green, LK Nieman, M Bagaria, M De Falco, M Egger, M Engman, M Moshesh, M Rees, M Sayyah-Melli, M Tristan, MA Lumsden, ME Fernandez-Mentoli, ME Parsanezhad, MG Munro, MS Melli, N Biglia, N Johnson, N Varun, O Gregoriou, O Muneyyirci-Delale, O Sadan, P Vercellini, PG Moorman, R D'Anna, R Hudecek, R Seracchioli, RC Reinsch, RL Barbieri, RW Shaw, S Campo, S Constantini, S Jirecek, S Jo Varghese, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, S Palomba, SE Bulun, SL Myers, SS Lim, T Simsek, TG Stovall, TG Stovall, TG Stovall, Toby Richards, WD Schlaff, YB Baytur   +119 more
core   +4 more sources

Shifting paradigms in uterine fibroids treatment: insights from current therapeutic approaches [PDF]

, 2023
This review examined the effectiveness of ulipristal acetate (UPA) compared to leuprolide acetate (LEU) in the treatment of symptomatic uterine fibroids. The primary objective was to analyze relevant studies that investigated the improvement of symptoms,
Cornejo, Morelia Yunuen López, García, Aurora Guadalupe García, Palacios, Avhril Alejandra Morales, Vespero, Fernando Hernández, Vázquez Ruvalcaba, Aranza   +4 more
core   +2 more sources

Effects of a novel estrogen-free, progesterone receptor modulator contraceptive vaginal ring on inhibition of ovulation, bleeding patterns and endometrium in normal women [PDF]

, 2012
BACKGROUND: Progesterone receptor modulators (PRMs) delivered by contraceptive vaginal rings provide an opportunity for development of an estrogen-free contraceptive that does not require daily oral intake of steroids.
Blithe, Diana, Brache, Vivian, Cochon, Leila, Croxatto, Horacio, Faundes, Anibal, Kumar, Narender, Kumar, Sushma, Miranda, Maria Jose, Mishell, Daniel, Nath, Anita, Reyes, Verónica, Sitruk-Ware, Regine, Sivin, Irving, Sussman, Heather, Tsong, Yun-Yen, Williams, Alistair   +15 more
core   +1 more source

Relating to the provision of information and other services relating to emergency contraception to sexual assault survivors (HB 747) [PDF]

, 2017
Population Research ...
Broussard, Kathleen
core   +1 more source

The Asian Society of Endometriosis and Adenomyosis guidelines for managing adenomyosis

, 2023
Reproductive Medicine and Biology, Volume 22, Issue 1, January/December 2023.
Tasuku Harada, Fuminori Taniguchi, Sun‐Wei Guo, Young Min Choi, Kutay Omer Biberoglu, Shaw‐Jenq Sean Tsai, Saeed Alborzi, Moamar Al‐Jefout, Amphan Chalermchokcharoenkit, Angela G. Sison‐Aguilar, Yoke‐Fai Fong, Hemantha Senanayake, Alexander Popov, Andon Hestiantoro, Yuval Kaufman   +14 more
wiley   +1 more source