Results 101 to 110 of about 1,219 (142)
Analysis of humeral condylar morphology in dogs with and without humeral intracondylar fissure
Veterinary Surgery, EarlyView.Abstract Objective To quantify the morphology of the humeral condyle in dogs with and without humeral intracondylar fissure (HIF). Study design Retrospective case control. Sample population A total of 171 elbows. Methods Computed tomography (CT) scans of elbows were retrospectively analyzed.
Emily Frapwell +7 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract We review our approach for undertaking microelectrode recordings from the posterior tibial nerve at the ankle, which has allowed us to identify, for the first time, the firing properties of muscle spindle endings in the intrinsic muscles of the foot and of cutaneous mechanoreceptors in the sole during unsupported standing.
Thomas P. Knellwolf +3 more
wiley +1 more source
Exploring neuronal mechanisms of osteosarcopenia in older adults
The Journal of Physiology, EarlyView.Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley +1 more source
Electrical stimulation of injured nerves promotes recovery in animals and humans
The Journal of Physiology, EarlyView.Abstract figure legend Poor functional recovery after surgical repair is frequently disappointing. In an experimental rat model, we found that by isolating the effects of prolonged motoneurone isolation from targets (prolonged axotomy), reduced regenerative capacity and prolonged isograft denervation, and muscle denervation each reduced regeneration ...
Tessa Gordon
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The first part of this experimental study showed that late adulthood (adults aged 65–75 years) is associated with reduced motor performance and learning of simple vigorous finger movements. The second part of the study shows that ballistic motor learning can be improved in older adults when a practice session is preceded by a ...
Jonas Rud Bjørndal +5 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.ABSTRACT Prenatal and neonatal presentations of multiple congenital anomalies are difficult to diagnose and are associated with an increased risk of lethality. The differential diagnosis of antenatal presentations of radial ray malformations includes Fanconi anemia (FA), an inherited bone marrow failure disorder associated with congenital anomalies in ...
Ethan M. Scott +5 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 7, July 2025.ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi +7 more
wiley +1 more source
Embryonic cranial cartilage defects in the Fgfr3Y367C/+ mouse model of achondroplasia
The Anatomical Record, Volume 308, Issue 7, Page 1893-1911, July 2025.Abstract Achondroplasia, the most common chondrodysplasia in humans, is caused by one of two gain of function mutations localized in the transmembrane domain of fibroblast growth factor receptor 3 (FGFR3) leading to constitutive activation of FGFR3 and subsequent growth plate cartilage and bone defects.
Susan M. Motch Perrine +9 more
wiley +1 more source
Muscle &Nerve, Volume 72, Issue 1, Page 15-33, July 2025.ABSTRACT Regeneration after peripheral nerve injury is often insufficient for functional recovery. Postoperative electrical stimulation (PES) following injury and repair significantly improves clinical outcomes; recently, conditioning electrical stimulation (CES), delivered before nerve injury, has been introduced as a candidate for clinical ...
Paige B. Hardy +4 more
wiley +1 more source
Muscle &Nerve, Volume 72, Issue 1, Page 49-55, July 2025.ABSTRACT Introduction/Aims Hypermetabolism and weight loss are established negative prognostic factors in amyotrophic lateral sclerosis (ALS). However, the role of individualized body composition parameters in predicting ALS progression has been underexplored. This study aimed to investigate the correlation between nutritional parameters, neurofilament
Aida Zulueta +10 more
wiley +1 more source