Results 41 to 50 of about 862,833 (296)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Ultra-low temperature grinding process and surface integrity of SiCp/Al material

open access: yesJin'gangshi yu moliao moju gongcheng
ObjectivesAs a new-generation high-performance structural material, silicon carbide particle-reinforced aluminum matrix composites (SiCp/Al) exhibit outstanding specific strength, wear resistance, and thermal stability, making them highly valuable in ...
Weicheng GUO   +3 more
doaj   +1 more source

Ultra-low temperature conservation of Brazilian Pine embryogenic cultures

open access: yesAnais da Academia Brasileira de Ciências, 2014
This study aimed to establish a cryopreservation protocol for embryogenic cultures of A. angustifolia, enabling the ex situ conservation of the species.
GRASIELA DEMARCHI   +5 more
doaj   +1 more source

Construction of a Versatile Ultra-Low Temperature Scanning Tunneling Microscope

open access: yes, 2007
We constructed a dilution-refrigerator (DR) based ultra-low temperature scanning tunneling microscope (ULT-STM) which works at temperatures down to 30 mK, in magnetic fields up to 6 T and in ultrahigh vacuum (UHV).
Fukuyama H.   +6 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Ultra-low power temperature sensor

open access: yes, 2023
We propose an architecture and circuit for temperature sensors integrated within systems on a chip. The circuit is based on special properties of devices when biased by a current with a particular dependence with temperature. We present results from a test circuit fabricated on a standard 0:8 ¹m CMOS technology which draws under 40 nA from a 1.6 V to 3.
Rossi, Conrado, Aguirre, Pablo
openaire   +1 more source

Ultra-low temperature silicon nitride photonic integration platform

open access: yesOptics Express, 2016
High-quality SiNx films with controllable low stress and low optical loss are deposited at ultra-low temperature (75 °C) using inductively coupled plasma chemical vapor deposition (ICP-CVD). Two kinds of integrated photonic structures have been demonstrated that exemplify its viability as a photonic integration platform.
Zengkai, Shao   +10 more
openaire   +2 more sources

Ultra-low-noise room-temperature quantum memory for polarization qubits

open access: yes, 2017
Here we show an ultra-low noise regime of operation in a simple quantum memory in warm Rb atomic vapor. By modelling the quantum dynamics of four-level room temperature atoms, we achieve fidelities >90% for single-photon level polarization qubits ...
Figueroa, Eden   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Quality analysis of fresh frozen plasma prepared by the improved ultra-low temperature storage box

open access: yesZhongguo shuxue zazhi
Objective To observe and analyze the influence of the improved ultra-low temperature storage box on the quality of fresh frozen plasma (FFP). Methods A total of 80 qualified whole blood samples (400 mL, O type not included) collected from July to ...
Jing ZHOU   +5 more
doaj   +1 more source

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