Results 71 to 80 of about 961,052 (305)

Geothermal power based ULTDH for cooling and heating purposes [PDF]

E3S Web of Conferences, 2019
Ultra-low temperature district heating systems facilitate use of waste and renewable heat sources. The article presents a possible scheme of operation and optimisation of small ultra-low temperature district heating system consisting of waste heat source,
Ciapała Bartłomiej, Janowski Mirosław
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Low-temperature cooling behavior of single-domain magnetite: Forcing of the crystallographic axes and interactions [PDF]

, 2006
Low-temperature cycling (LTC) of magnetic remanences carried by rocks has become a standard technique in paleomagnetism, rock magnetism, and environmental magnetism as a means of identifying mineralogy and grain size.
Williams, Wyn; id_orcid
core   +1 more source

Preparation of α-MnMoO4 at ultra-low temperature on an organic substrate

Materials Research Bulletin, 2013
Highlights: ► A film of α-MnMoO{sub 4} nanorods was prepared on paper. ► The film was prepared by a solution reaction and subsequent dehydration at 220 °C. ► The average film thickness was approximately 60 μm. ► The relative permittivity of the prepared α-MnMoO{sub 4} film was 12 at 1 GHz.
Jantunen Heli, Juuti Jari, Myllymäki Sami, Kähäri Hanna Henriikka   +3 more
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Ultra-low power metal oxide gas sensor on plastic foil [PDF]

, 2009
We report on the design and fabrication of ultra-low power metal-oxide (MOX) gas sensors on plastic foils envisioning their fabrication at large scale and low cost. A complete sensor solution is presented including its packaging at the foil level and the
Raible, S., N.F. de Rooij, L. Yue, S. Raible, D. Briand, Briand, D., Yue, L., Courbat, J., de Rooij, N. F., J. Courbat   +9 more
core   +1 more source

Research on the Material Characteristics and Loss Calculation Method of Cryogenic Permanent Magnet Motor Stator for LNG Pump

Energies
This paper explores the applicability of cryogenic permanent magnet motor stator materials for LNG pumps. First, this study selected four kinds of silicon steel sheets for motor stators tested at room temperature and ultra-low temperature and obtained ...
Shuqi Liu, Baojun Ge, Likun Wang, Yue Wang   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Ultra-low power temperature sensor

, 2023
We propose an architecture and circuit for temperature sensors integrated within systems on a chip. The circuit is based on special properties of devices when biased by a current with a particular dependence with temperature. We present results from a test circuit fabricated on a standard 0:8 ¹m CMOS technology which draws under 40 nA from a 1.6 V to 3.
Rossi, Conrado, Aguirre, Pablo
openaire   +1 more source