Results 81 to 90 of about 166,094 (382)
Importance Recent studies have shown that Friedewald underestimates low-density lipoprotein cholesterol (LDL-C) at lower levels, which could result in undertreatment of high-risk patients.
S. Martin+13 more
semanticscholar +1 more source
Deinococcus radiodurans‐derived extracellular vesicles (R1‐EVs) provide radioprotection against total‐body irradiation‐induced acute radiation syndrome in mice. R1‐EVs mitigate oxidative damage by scavenging free radicals, promoting intestinal repair, enhancing hematopoietic function, and modulating immune responses. This study highlights the potential
Jeong Moo Han+7 more
wiley +1 more source
Comparison of Exosome Isolation Techniques for Clinical Applications
Exosomes are extracellular vesicles with significant potential in clinical applications, particularly in diagnostics and therapeutics. Effective exosome isolation is critical to ensuring their functionality and integrity, especially for clinical uses ...
Nadiar M. Mussin+6 more
doaj +1 more source
Nitrogen Oxyanion-dependent Dissociation of a Two-component Complex That Regulates Bacterial Nitrate Assimilation [PDF]
Nitrogen is an essential nutrient for growth and is readily available to microbes in many environments in the form of ammonium and nitrate. Both ions are of environmental significance due to sustained use of inorganic fertilizers on agricultural soils ...
Goldman+6 more
core +1 more source
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang+8 more
wiley +1 more source
Production- and Purification-Relevant Properties of Human and Murine Cytomegalovirus
There is a large unmet need for a prophylactic vaccine against human cytomegalovirus (HCMV) to combat the ubiquitous infection that is ongoing with this pathogen.
Sanda Ravlić+4 more
doaj +1 more source
Urinary cholesterol: its association with a macromolecular protein- lipid complex [PDF]
The cholesterol-containing complexes in the urine of normal subjects and patients with diseases accompanied by hyperexcretion of urinary cholesterol were characterized. In normal subjects, the major portion of the recovered urinary cholesterol was eluted
Jüngst, Dieter+3 more
core
Biophysical evidence for intrinsic disorder in the C-terminal tails of the epidermal growth factor receptor (EGFR) and HER3 receptor tyrosine kinases [PDF]
The epidermal growth factor receptor (EGFR)/ErbB family of receptor tyrosine kinases includes oncogenes important in the progression of breast and other cancers, and they are targets for many drug development strategies.
Bose, Ron+5 more
core +2 more sources
Ultracentrifugation (UC) is recognized as a robust approach for the isolation of extracellular vesicles (EVs). However, recent studies have highlighted limitations of UC including low recovery efficiencies and aggregation of EVs that could impact ...
Phat Duong+3 more
semanticscholar +1 more source
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan+3 more
wiley +1 more source