Results 101 to 110 of about 156,660 (284)

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li   +15 more
wiley   +1 more source

The effect of NOM characteristics and membrane type on microfiltration performance [PDF]

open access: yes, 2007
Efforts to understand and predict the role of different organic fractions in the fouling of low-pressure membranes are presented. Preliminary experiments with an experimental apparatus that incorporates automatic backwashing and filtration over several ...
Bolto, Brian   +3 more
core  

Dead-end filtration of yeast suspensions: correlating specific resistance and flux data using artificial neural networks [PDF]

open access: yes, 2006
The specific cake resistance in dead-end filtration is a complex function of suspension properties and operating conditions. In this study, the specific resistance of resuspended dried bakers yeast suspensions was measured in a series of 150 experiments ...
Foley, Greg, Ní Mhurchú, Jenny
core   +1 more source

Islet Amyloid Polypeptide Modelled to Simulate Diabetes Co‐Oligomerized with β‐Amyloid 1‐42 Reproducing the Pathological Cascade of Alzheimer's Disease in Human Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
Human islet amyloid polypeptide (hIAPP) was used to mimic T2DM, and Aβ42‐hIAPP co‐oligomers were delivered into the human mature cerebral organoids (COs), which reproduce typical AD pathology and significant neuronal death more closely resembling that of AD patients.
Jin Yan   +6 more
wiley   +1 more source

Characterization of new membrane materials by means of fouling experiments Adsorption of bsa on polyetherimide-polyvinylpyrrolidone membranes [PDF]

open access: yes, 1991
The hydrophilicity of polyetherimide-polyvinylpyrrolidone (PEI-PVP) microfiltration membranes can be adjusted by means of a suitable post-treatment. The influence of the nature of the membrane surface on fouling properties was studied using permeation ...
Beerlage, M.A.M.   +5 more
core   +2 more sources

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

open access: yesAdvanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi   +15 more
wiley   +1 more source

Fractionation of Glycomacropeptide from Whey Using Positively Charged Ultrafiltration Membranes

open access: yesFoods, 2018
Fractionation of the bovine glycomacropeptide (GMP) from the other proteins in cheese whey was examined using ultrafiltration membranes surface modified to contain positively charged polymer brushes made of polyhexamethylene biguanide.
Abhiram Arunkumar, Mark R. Etzel
doaj   +1 more source

Assessment and Management of Hypertension among Patients on Peritoneal Dialysis [PDF]

open access: yes, 2019
Approximately 7%-10% of patients with ESKD worldwide undergo peritoneal dialysis (PD) as kidney replacement therapy. The continuous nature of this dialytic modality and the absence of acute shifts in pressure and volume parameters is an important ...
Agarwal, Rajiv   +3 more
core   +1 more source

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong   +9 more
wiley   +1 more source

Fouling and Rejection Behaviour of Ultrafiltration for Oil in Water Emulsion Separation [PDF]

open access: yes, 2012
Oily waste water has been generated from food, automotive, metal processing industries as well as petroleum exploration and refinery. Polyethersulfone ultrafiltration membrane was investigated for treatment of oil in water emulsion.
Agus , Hadiyarto   +2 more
core  

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