Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen +7 more
wiley +1 more source
Effects of improved ultrafiltration on serum level of IL-6 and TNF-a, HCT, and cardiopulmonary function in patients with extracorporeal circulation in valve replacement. [PDF]
Ning G, Fu L, Zhou G.
europepmc +1 more source
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira +9 more
wiley +1 more source
Clinical benefits of icodextrin in peritoneal dialysis: Evidence from a multicenter, prospective, randomized controlled trial. [PDF]
Li Y, Yang C, Zhou Z.
europepmc +1 more source
Novel Wide‐Spectrum Virucidal Lipid Nanoparticles
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins +10 more
wiley +1 more source
Operationalizing Home Blood Pressure Monitoring for Dialysis Patients: An Effectiveness-Implementation Hybrid Study. [PDF]
Obi Y +8 more
europepmc +1 more source
High‐Yield Assembly of Plasmon‐Coupled Nanodiamonds Using DNA Origami for Tuned Emission
Engineering assemblies of single‐photon emitters and plasmonic elements with nanometer precision opens pathways for quantum sensing and photonics applications. A surface functionalization strategy is established for grafting DNA onto nanodiamonds, and their placement on DNA origami is optimized to achieve yields above 50%.
Niklas Hansen +7 more
wiley +1 more source
Exploring the Novel Pancreatic Lipase-Inhibitory Peptides in <i>Chlorella pyrenoidosa</i>: Preparation, Purification, Identification, and Molecular Docking. [PDF]
Wang D +6 more
europepmc +1 more source
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan +10 more
wiley +1 more source
Peritoneal dialysis and heart failure. [PDF]
Hsu CM, Weiner DE, McCallum W.
europepmc +1 more source

