A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv +16 more
wiley +1 more source
Ultrasound-mediated structural and chemical modifications in wheat proteins and their impact on functional and storage properties: a review. [PDF]
Garg K, Sinha S, Kaur K, Qadri OS.
europepmc +1 more source
The sunscreen‐inspired nano‐pesticide, MCB@URFSL, provides UV‐shielding, enhanced rainfastness, and laccase‐responsive delivery for improved fungicidal efficacy and high ecological safety. ABSTRACT Fungicides are a crucial tool for protecting crops and ensuring consistent food supply.
Jin Yan +10 more
wiley +1 more source
Clinical-scale manufacturing of CD137+ enriched tumor-reactive T cells for glioblastoma in the CliniMACS Prodigy. [PDF]
Riabinska A +26 more
europepmc +1 more source
An Intravesical Akkermansia muciniphila‐Based Chemo‐Immunotherapeutic Platform for Bladder Cancer
Pasteurized Akkermansia muciniphila is engineered into an intravesical F127/doxorubicin platform that couples localized chemotherapy with immune remodeling. By inducing apoptosis, ferroptosis, and immunogenic cell death, this chemo‐immunotherapeutic system enhances dendritic‐cell maturation, antigen cross‐presentation, and tumor‐specific CD8+ T‐cell ...
Rongkang Li +11 more
wiley +1 more source
Comparison of Laser and Conventional Root Canal Disinfection Protocols in an dual-biofilm in-vitro model. [PDF]
Wang J, Li W, Lan W, Ye L, Gao B.
europepmc +1 more source
A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Beyond the Conventional: Successful Negotiation and Management of the Middle Mesial Canal. [PDF]
Rasheed Moopan R +4 more
europepmc +1 more source
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Monitoring of oxidative stress and acute phase proteins following testes exposure with ultrasound waves in cats. [PDF]
Hashempur Z +9 more
europepmc +1 more source

