Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Advanced Science, EarlyView.Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source
Effect of irrigant type, activation method, and contact time on dentin diffusion and ultrastructure. [PDF]
Braz Oral ResCosta VASM +9 more
europepmc +1 more source
Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice
Advanced Science, EarlyView.A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li +12 more
wiley +1 more source
Comparison of the ultrasonic, Masserann, and BTR-pen techniques for removing fractured instruments with dental microscope: a CBCT-based in vitro study. [PDF]
Acta Odontol ScandBalkanlıoğlu E, Kamalak A, Güner B.
europepmc +1 more source
One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections
Advanced Science, EarlyView.Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong +11 more
wiley +1 more source
Energy sources in percutaneous surgery. Are lasers ready to become the gold standard? A narrative review. [PDF]
Int Braz J UrolPuppin JPL +10 more
europepmc +1 more source
Advanced Science, EarlyView.Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian +10 more
wiley +1 more source
Prognosis of Periapical Lesions Treated by Activated Disinfection (PUI, Laser) Without the Use of Systemic Antibiotics: Systematic Review and Meta-Analysis. [PDF]
J Clin MedFernández-Moreno P +7 more
europepmc +1 more source
Advanced Science, EarlyView.Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang +10 more
wiley +1 more source
Ultrasonic debridement promotes wound healing and enhances infection control compared with surgical debridement in diabetic foot ulcers: a propensity score-matched retrospective study. [PDF]
Am J Transl ResSong D, Chen H, Shao D.
europepmc +1 more source