Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Ultrasound vs. Fluoroscopy Guided Erector Spinae Plane Block in Postherpetic Neuralgia: A Prospective Study. [PDF]
Ozalp B, Yolcu G, Uyar M, Eyigor C.
europepmc +1 more source
Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Pseudoaneurysm of the Medial Genicular Artery as a Rare Cause of Recurrent Knee Swelling - A Case Report. [PDF]
Thankappan A +5 more
europepmc +1 more source
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng +10 more
wiley +1 more source
Pediatric Digital Artery Pseudoaneurysm From Repetitive Compression While Gripping Toys. [PDF]
Uno K +5 more
europepmc +1 more source
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Case Report: Lymphatic malformation in a paediatric patient with a 7-year follow-Up. [PDF]
Wang L, Guo L.
europepmc +1 more source
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Transarterial embolization for chronic wrist pain: a preliminary study of feasibility, safety, and pain reduction. [PDF]
Min J +5 more
europepmc +1 more source

