Results 171 to 180 of about 32,958 (224)

Cardiomyocyte‐Enriched USP20 Ameliorates Pathological Cardiac Hypertrophy by Targeting STAT3 Deubiquitination

Advanced Science, EarlyView.
Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong, Shanshan Dai, Fan Yu, Guo‐Ping Shi, Qinyan Gong, Yucong Zhang, Jingsi Duan, Zhengyin Lou, Zhixuan Tang, Fuzhe Gong, Derong Chen, Liya Hou, Xinyang Hu, Jinghai Chen, Jian'an Wang, Deling Yin   +15 more
wiley   +1 more source

Scrotal hematoma caused by femoral artery puncture during ablation. [PDF]

J Arrhythm
Muto K, Naganuma T, Mori H, Ikeda Y, Kato R.   +4 more
europepmc   +1 more source

Biomimetic MOF Nanocarrier‐Mediated Synergistic Delivery of Mitochondria and Anti‐Inflammatory miRNA to Alleviate Acute Lung Injury

Advanced Science, EarlyView.
A biomimetic MOF nanocarrier for macrophage‐targeting delivery of both mitochondria and anti‐miR‐127 is designed with an aim to revitalize macrophages and remold the inflammatory microenvironment for treating acute lung injury. By leveraging the macrophages‐targeting property and pH‐responsiveness, ZIF‐8 nanocarriers facilitated efficient delivery of ...
Xin Shou, Changjiang Chen, Hangjie Ying, Zhiyun Liu, Lingyao Zeng, Qiujie Li, Lanjie Lei, Bingyong Mao, Wei Zhang, Shumao Cui, Liyun Shi   +10 more
wiley   +1 more source

Diagnosis and Management of Inadvertent Iliac Vein Injury During Structural Heart Interventions. [PDF]

JACC Case Rep
Sava RI, Zendjebil S, Sochala M, Djebbar M, Tence N, Garot P.   +5 more
europepmc   +1 more source

Bioinspired Mechanisms and Actuation of Soft Robotic Crawlers

Advanced Science, EarlyView.
Researchers have been developing soft materials and robotic crawlers inspired by soft‐bodied animals to mimic effective crawling in complex environments. This review explores the state‐of‐the‐art in soft crawlers, highlighting the interaction between materials, crawling mechanisms, actuation, and applications. The review concludes by providing insights
Min Pan, Miaomiao Liu, Jiayi Lei, Yunyi Wang, Changhong Linghu, Chris Bowen, K. Jimmy Hsia   +6 more
wiley   +1 more source

Which localization method is optimal in ESWL: fluoroscopy or ultrasonography? [PDF]

BMC Urol
Baba D, Ekici N, Taşkıran AT, Şenoğlu Y, Yüksel A, Başaran E, Özel MA, Balık AY.   +7 more
europepmc   +1 more source

Endothelial PD‐1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development

Advanced Science, EarlyView.
Vascular endothelial cells are fundamental for angiogenesis and brain development. This study reveals that endothelial programmed cell death 1 (PD‐1) is critical for cerebral angiogenesis and blood brain barrier (BBB) maturation. It also mediates interaction with oligodendrocyte precursor cells (OPCs), modulating OPCs differentiation and myelination ...
Tingting He, Mengtian Zhang, Jie Qin, Yanyan Wang, Sihan Li, Chaoyi Du, Jianwei Jiao, Fen Ji   +7 more
wiley   +1 more source

A 15-year-old teenager with refractory intracranial hypertension due to scalp arteriovenous fistula: case report. [PDF]

BMC Neurol
Zhang Q, Gu Y, Hua Y, Zhang P, Chen J, Qu X, Ji X, Duan J.   +7 more
europepmc   +1 more source

Leucine‐Rich Repeat‐Containing G Protein‐Coupled Receptor 6 Ameliorates Pressure Overload‐Induced Cardiac Hypertrophy by Regulating Cardiomyocyte Metabolic Reprogramming

Advanced Science, EarlyView.
LGR6 overexpression ameliorates cardiac hypertrophy by regulating metabolic reprogramming through USP4‐PPARα pathway. Abstract Metabolic reprogramming is a pivotal mechanism in the pathogenesis of pathological cardiac hypertrophy. Leucine‐rich repeat‐containing G protein‐coupled receptor 6 (Lgr6) has emerged as a significant player in cardiovascular ...
Mengmeng Zhao, Jianfang Liu, Shanshan Peng, Zihui Zheng, Siqi Liu, Jun Wan, Yao Xu, Menglong Wang   +7 more
wiley   +1 more source

Training of Radiology Residents in Singapore. [PDF]

Korean J Radiol
Ho FCH, Tan CH, Lim TC, Too CW, Low HM, Goh CXY.   +5 more
europepmc   +1 more source