Abstract Cryo‐Focused Ion Beam Scanning Electron Microscopy (cryoFIB‐SEM) using samples fixed by high‐pressure freezing uniquely enables high‐resolution cryo‐volume Electron Microscope (cvEM) images of cell ultrastructure to be obtained from whole cells and complex tissues in their near native state. As the freezing process also preserves fluorescence,
Maryna Kobylynska +10 more
wiley +1 more source
Preliminary ultrastructural analysis suggests phenotype-specific myofiber alterations in idiopathic inflammatory myopathies. [PDF]
Aguilar-Vazquez A +24 more
europepmc +1 more source
Advancing collagen‐related pathology assessment through second‐harmonic generation imaging
Abstract Collagen remodelling and dysregulation are the hallmarks of diverse pathological conditions. In this context, second‐harmonic generation (SHG) imaging has emerged as a powerful label‐free modality for assessing collagen. This offers submicron resolution, intrinsic optical sectioning, and deeper imaging capabilities without the need for ...
Jackson Rodrigues +7 more
wiley +1 more source
Correction: Kim et al. Anti-Inflammatory Response and Muscarinic Cholinergic Regulation During the Laxative Effect of <i>Asparagus cochinchinensis</i> in Loperamide-Induced Constipation of SD Rats. <i>Int. J. Mol. Sci.</i> 2019, <i>20</i>, 946. [PDF]
Kim JE +9 more
europepmc +1 more source
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó +4 more
wiley +1 more source
Correction: TRPV1 deletion in male mice alters cardiomyocyte ultrastructure without affecting baseline cardiac function. [PDF]
Tessier N +14 more
europepmc +1 more source
In this study we show for the first time that the human basilar membrane contains elastin produced by the so‐called tympanic covering layer. It is believed to play an important functional role in human cochlear tuning, particularly low frequencies linked to our remarkable speech and music perception.
Wei Liu +9 more
wiley +1 more source
Coordinated Bone-Muscle Axis Association in South China Carp (<i>Cyprinus carpio rubrofuscus</i>) with Low Bone Mineral Density: An Integrated Analysis of Muscle Texture, Nutrition, Ultrastructure, and Proteomics. [PDF]
Zhao K +6 more
europepmc +1 more source
Bioengineered tissue constructs are vital technologies employed in in vitro testing of both fundamental biological principles and industrial screening practices. Current approaches to modelling the nasal mucosa in vitro are not representative and are associated with limitations that impact their reliability and predictive value.
Steven Bradbury +5 more
wiley +1 more source
Abstract Purpose There is a need for effective solutions for the persistent prevalence of denture stomatitis (DS) in denture‐wearing populations. This study assessed the impact of nanohydroxyapatite (nanoHAP) nanoparticles on Candida albicans biofilm formation on milled polymethylmethacrylate (PMMA) denture bases.
Cynthia U. Udeh +8 more
wiley +1 more source

